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Like Vince said, I would guestimate that your night sweats are a result of your E2 levels naturally dropping at night, and your body is shedding some of the excess water weight it is retaining. Elevated E2 can also cause testicles and penis to shrink/shrivel, as well as kill and sometimes spike libido. I would do what you have to to start monitoring this hormone, it's essential to the success of your treatment.