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Testosterone Replacement, Low T, HCG, & Beyond
When Testosterone Is Not Enough
Iron on TRT? - No libido
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<blockquote data-quote="bvictor" data-source="post: 235567" data-attributes="member: 43217"><p>26m who has struggled on TRT for a long time.</p><p></p><p>In summer 2021 was prescribed test cypionate which immediately causes complete loss of libido, which only returned about 6 weeks after cessation of treatment.</p><p></p><p>Testosterone did not naturally recover (although libido did), and resumed treatment this time with scrotal cream through Defy in Jan 2022. Libido was mostly alright (on and off), but completely died again in August. I can't figure out what changed, besides possibly the use of anavar, 25mg/day, which crushed my shbg. However, my libido was mostly fine on the drug for 9 weeks prior, and only died in August.</p><p></p><p>Also supplement 100mcg T4 and 35mcg T3 in the morning, and 100mg pregnenolone, and 4mg Naltrexone at night.</p><p></p><p>My frequent blood tests have mostly been normal, although after crushing shbg it seems total testosterone is much lower than at the beginning of treatment, despite remaining on 4 clicks of the 200mg/ml cream in the morning.</p><p></p><p>My dhea is ~150 (138-275), but has been around this level for a long time, including when my libido was good.</p><p></p><p>Recently tested Iron, which has come down a lot since it was last tested in April:</p><p></p><p>Iron Bind.Cap.(TIBC) <strong>326 </strong>Prior (<strong>285)</strong> 04/12/2022 ug/dL 250-450</p><p>UIBC01 <strong>278</strong> Prior(<strong>203</strong>) 04/12/2022 ug/dL 111-343 </p><p>Iron01 <strong>48</strong> Prior(<strong>82</strong>) 04/12/2022 ug/dL 38-169</p><p>Iron Saturation <strong>15</strong> Prior(<strong>29</strong>) 04/12/2022 % 15-55</p><p></p><p>Could low iron explain my symptoms? Would it be appropriate to supplement? Tad surprising given I eat a good amount of fish, meat, shellfish, and even liver.</p><p></p><p>Also trialed hcg without success, and really at my wits end with respect to libido here. Unfortunately lack of libido seems to correlate with a general anhedonia for me, and I'm contemplating coming off trt entirely again.</p><p></p><p>Has anybody else lost libido over time on cream or after a long trial of dht derivatives (anavar)? I speculate that if I can get my SHBG to return from 17 atm back to 30 or 40 where it sat prior it could fix my issue?</p></blockquote><p></p>
[QUOTE="bvictor, post: 235567, member: 43217"] 26m who has struggled on TRT for a long time. In summer 2021 was prescribed test cypionate which immediately causes complete loss of libido, which only returned about 6 weeks after cessation of treatment. Testosterone did not naturally recover (although libido did), and resumed treatment this time with scrotal cream through Defy in Jan 2022. Libido was mostly alright (on and off), but completely died again in August. I can't figure out what changed, besides possibly the use of anavar, 25mg/day, which crushed my shbg. However, my libido was mostly fine on the drug for 9 weeks prior, and only died in August. Also supplement 100mcg T4 and 35mcg T3 in the morning, and 100mg pregnenolone, and 4mg Naltrexone at night. My frequent blood tests have mostly been normal, although after crushing shbg it seems total testosterone is much lower than at the beginning of treatment, despite remaining on 4 clicks of the 200mg/ml cream in the morning. My dhea is ~150 (138-275), but has been around this level for a long time, including when my libido was good. Recently tested Iron, which has come down a lot since it was last tested in April: Iron Bind.Cap.(TIBC) [B]326 [/B]Prior ([B]285)[/B] 04/12/2022 ug/dL 250-450 UIBC01 [B]278[/B] Prior([B]203[/B]) 04/12/2022 ug/dL 111-343 Iron01 [B]48[/B] Prior([B]82[/B]) 04/12/2022 ug/dL 38-169 Iron Saturation [B]15[/B] Prior([B]29[/B]) 04/12/2022 % 15-55 Could low iron explain my symptoms? Would it be appropriate to supplement? Tad surprising given I eat a good amount of fish, meat, shellfish, and even liver. Also trialed hcg without success, and really at my wits end with respect to libido here. Unfortunately lack of libido seems to correlate with a general anhedonia for me, and I'm contemplating coming off trt entirely again. Has anybody else lost libido over time on cream or after a long trial of dht derivatives (anavar)? I speculate that if I can get my SHBG to return from 17 atm back to 30 or 40 where it sat prior it could fix my issue? [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
When Testosterone Is Not Enough
Iron on TRT? - No libido
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