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It does sound like you’re treating the wrong thing which is why it seems like you’re on a roller coaster ride and can never find balance. Similar to Cushing’s disease, an increase in all steroid hormones, TRT increases aldosterone produced in adrenal glands, which enters the kidneys, and tells the kidneys to absorb more sodium and sodium, carries water. This leads to fluid retention.


This fluid retention can cause blood pressure spikes. The AI is acting like a diuretic, decreasing fluid retention and then estrogen crashes, then several days later you experienced the E2 rebound effect.


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