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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Insomnia... Xanax? Might try TRT again.....here we go again
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<blockquote data-quote="madman" data-source="post: 198268" data-attributes="member: 13851"><p>Still, relying upon/using the piss poor inaccurate direct immunoassay for FT?</p><p></p><p>In every set of labs you have ever posted on here you keep getting your FT tested using an inaccurate assay yet TT and estradiol using (LC/MS-MS).....go figure.</p><p></p><p>As I have stated numerous times on here that although TT is important to know FT is what truly matters as it is the active unbound fraction of testosterone responsible for the positive effects.</p><p></p><p>Depending on where your TT sits even with high/highish SHBG your FT may not be as low as you think.</p><p></p><p>The only way to know where it truly sits is to have it tested using an accurate assay such as the gold standard Equilibrium Dialysis or Ultrafiltration.</p><p></p><p>This should be a given and even more so in cases of altered SHBG!</p><p></p><p>Regardless when looking over labs from some of your previous trt protocols 160 mg/week T (80 mg every 3.5 days), you were hitting a trough TT 1000s and high FT (using the piss poor direct immunoassay) and that was with high SHBG 61.3 nmol/L let alone your e2 (LC/MS-MS) was through the roof 75.3.</p><p></p><p>Even then with a trough TT 1000s even with a high SHBG 61.3 nmol/L, I would put money on it that if your FT was tested using an accurate assay (ED or UF) it would be much higher than you think.</p><p></p><p>No point in trying to manage a protocol when you have absolutely no idea where your FT level truly sits on such.</p><p></p><p>FT 5-10 ng/dL would be considered low.</p><p></p><p>FT 16-31 ng/dL would be considered healthy.</p><p></p><p>Most men will do well with FT 20-30 ng/dL.</p><p></p><p>Did you see the FT level (almost 50 ng/dL) [USER=843]@Vince[/USER] is hitting with a TT 1300 and highish SHBG (almost 50 ng/dL)?</p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/my-most-recent-labs.23112/#post-198257[/URL]</p><p></p><p>Many on here let alone lurking on the other forums would have you think that men with high/highish SHBG need to be running those you know absurdly high trough TT 1500-2000 ng/dL to achieve a healthy FT level.....LMFAO!</p></blockquote><p></p>
[QUOTE="madman, post: 198268, member: 13851"] Still, relying upon/using the piss poor inaccurate direct immunoassay for FT? In every set of labs you have ever posted on here you keep getting your FT tested using an inaccurate assay yet TT and estradiol using (LC/MS-MS).....go figure. As I have stated numerous times on here that although TT is important to know FT is what truly matters as it is the active unbound fraction of testosterone responsible for the positive effects. Depending on where your TT sits even with high/highish SHBG your FT may not be as low as you think. The only way to know where it truly sits is to have it tested using an accurate assay such as the gold standard Equilibrium Dialysis or Ultrafiltration. This should be a given and even more so in cases of altered SHBG! Regardless when looking over labs from some of your previous trt protocols 160 mg/week T (80 mg every 3.5 days), you were hitting a trough TT 1000s and high FT (using the piss poor direct immunoassay) and that was with high SHBG 61.3 nmol/L let alone your e2 (LC/MS-MS) was through the roof 75.3. Even then with a trough TT 1000s even with a high SHBG 61.3 nmol/L, I would put money on it that if your FT was tested using an accurate assay (ED or UF) it would be much higher than you think. No point in trying to manage a protocol when you have absolutely no idea where your FT level truly sits on such. FT 5-10 ng/dL would be considered low. FT 16-31 ng/dL would be considered healthy. Most men will do well with FT 20-30 ng/dL. Did you see the FT level (almost 50 ng/dL) [USER=843]@Vince[/USER] is hitting with a TT 1300 and highish SHBG (almost 50 ng/dL)? [URL unfurl="true"]https://www.excelmale.com/forum/threads/my-most-recent-labs.23112/#post-198257[/URL] Many on here let alone lurking on the other forums would have you think that men with high/highish SHBG need to be running those you know absurdly high trough TT 1500-2000 ng/dL to achieve a healthy FT level.....LMFAO! [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Insomnia... Xanax? Might try TRT again.....here we go again
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