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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Injection frequency
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<blockquote data-quote="Cataceous" data-source="post: 167135" data-attributes="member: 38109"><p>This is the mythology I'm trying to debunk. Differing SHBG levels do not change the apparent half-lives of injected testosterone esters. As I've explained before, after you inject a testosterone ester you have this oily depot in muscle or under the skin. The depot slowly dissolves, releasing the testosterone ester, which eventually gets into the bloodstream, where enzymes cleave the ester and release the pure testosterone. Only then is the testosterone free to interact with other molecules, such as SHBG. The apparent half-life of a testosterone ester is determined by how fast its depot dissolves. This is not influenced by SHBG.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 167135, member: 38109"] This is the mythology I'm trying to debunk. Differing SHBG levels do not change the apparent half-lives of injected testosterone esters. As I've explained before, after you inject a testosterone ester you have this oily depot in muscle or under the skin. The depot slowly dissolves, releasing the testosterone ester, which eventually gets into the bloodstream, where enzymes cleave the ester and release the pure testosterone. Only then is the testosterone free to interact with other molecules, such as SHBG. The apparent half-life of a testosterone ester is determined by how fast its depot dissolves. This is not influenced by SHBG. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Injection frequency
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