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Again although TT is important to know FT is what truly matters as it is the active unbound fraction of T responsible for the positive effects.


Top it off that we always need to test at the true trough lowest point before your next injection.


You were hitting a whopping TT 1200 ng/dL (100 mgT/week) and robust TT 635 ng/dL (50 mg T/week) and you have normalish SHBG but not sure where it sat on your 100 mg/week  protocol.


How many days post-injection on both protocols 50/100 mg T were labs done?


Going to be a big difference in peak--->trough when injecting once weekly.


Need to know what trough FT level you were truly hitting before jumping to any conclusions as to whether your dose of T is possibly too high or too low!


Common starting dose is 100 mg T/week.


Yes some may start on <100 mg/week but it is far from common.


Rare that anyone would be started on 50 mg T injected once weekly and even if the  starting dose 100 mg is eventually titrated  down most are still injecting more than 50 mg T/week.





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