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Mental Health
Inflammation, motivation and dopamine
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<blockquote data-quote="Will Brink" data-source="post: 154905" data-attributes="member: 2074"><p>There's a fascinating connection between inflammation, dopamine, and motivation:</p><p></p><p>"Why do we feel listless when we are recovering from an illness? The answer is, apparently, that low-grade chronic inflammation interferes with the dopaminergic signaling system in the brain that motivates us to do things.</p><p></p><p>This was reported in a new paper published in the journal <em><a href="https://www.cell.com/trends/cognitive-sciences/fulltext/S1364-6613(19)30066-X?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS136466131930066X%3Fshowall%3Dtrue" target="_blank">Trends in Cognitive Sciences</a></em>.</p><p></p><p></p><p>The research carried out at Emory University explains the links between the reduced release of dopamine in the brain, the motivation to do things, and the presence of an inflammatory reaction in the body. It also presents the possibility that this is part of the body’s effort to optimize its energy expenditure during such inflammatory episodes, citing evidence gathered during their study.</p><p></p><p></p><p>The authors also published an experimental framework based on computational tools, devised to test the theory.</p><p></p><p></p><p>The underlying hypothesis is that the body needs more energy to heal a wound or overcome an infection, for instance, both of which are associated with low-grade inflammation. To ensure that energy is available, the brain uses an adaptive technique to reduce the natural drive to perform other tasks which could potentially drain away the energy needed for healing. This is essentially a recalibration of the specialized reward neurons in the motivation center of the brain, so that ordinary tasks no longer feel like they’re worth doing.'</p><p></p><p>Cont:</p><p></p><p><a href="https://www.news-medical.net/news/20190605/Chronic-inflammation-removes-motivation-by-reducing-dopamine-in-the-brain.aspx?" target="_blank">Chronic inflammation removes motivation by reducing dopamine in the brain</a></p></blockquote><p></p>
[QUOTE="Will Brink, post: 154905, member: 2074"] There's a fascinating connection between inflammation, dopamine, and motivation: "Why do we feel listless when we are recovering from an illness? The answer is, apparently, that low-grade chronic inflammation interferes with the dopaminergic signaling system in the brain that motivates us to do things. This was reported in a new paper published in the journal [I][URL='https://www.cell.com/trends/cognitive-sciences/fulltext/S1364-6613(19)30066-X?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS136466131930066X%3Fshowall%3Dtrue']Trends in Cognitive Sciences[/URL][/I]. The research carried out at Emory University explains the links between the reduced release of dopamine in the brain, the motivation to do things, and the presence of an inflammatory reaction in the body. It also presents the possibility that this is part of the body’s effort to optimize its energy expenditure during such inflammatory episodes, citing evidence gathered during their study. The authors also published an experimental framework based on computational tools, devised to test the theory. The underlying hypothesis is that the body needs more energy to heal a wound or overcome an infection, for instance, both of which are associated with low-grade inflammation. To ensure that energy is available, the brain uses an adaptive technique to reduce the natural drive to perform other tasks which could potentially drain away the energy needed for healing. This is essentially a recalibration of the specialized reward neurons in the motivation center of the brain, so that ordinary tasks no longer feel like they’re worth doing.' Cont: [URL="https://www.news-medical.net/news/20190605/Chronic-inflammation-removes-motivation-by-reducing-dopamine-in-the-brain.aspx?"]Chronic inflammation removes motivation by reducing dopamine in the brain[/URL] [/QUOTE]
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Mental Health
Inflammation, motivation and dopamine
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