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Message: <blockquote data-quote="Jinzang" data-source="post: 95438" data-attributes="member: 12925">This study adds to growing evidence that cardiovascular risk from TRT may be less than once feared. The increased risk of sleep apnea in men using TRT is noteworthy. The study strengths include the large number of healthy and young men exposed to TRT. Limitations include the retrospective study design inability to account for granular details of TRT use such as dosage, specific forms of TRT and serum testosterone levels pre- and post-TRT.The evidence piles up that TRT is protective against heart disease. The <a href="http://onlinelibrary.wiley.com/doi/10.1111/bju.14149/abstract" target="_blank">abstract of this observational study</a> says:.</blockquote>