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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Imbalance of testosterone/estradiol promotes male CHD development
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<blockquote data-quote="Cataceous" data-source="post: 260898" data-attributes="member: 38109"><p>Personally I prefer the E2/T ratio, either by weight or molar concentration. In any case, this study appears to use T in ng/dL divided by (10 times E2 in pg/mL). No explanation why—perhaps just to make nice numbers. Controls had T = 611.42 and E2 = 36.35. CHD cases had T = 522.44 and E2 = 20.73. I assume the ratios were calculated before averaging, so the ratio of the averages is not equal to the average of the ratios. That is, in the CHD group 522.44 / 10 / 20.73 = 2.52, which is different from the stated ratio of 3.28.</p><p></p><p>Looking at their results as E2/T, the control is 0.59%, while the CHD group is 0.30%. I've been giving a normal range for E2/T as something like 0.3-0.6%, so their control does seem to be on the high side. It's probably best not to focus too hard on the absolute numbers. Instead the message is that less estradiol relative to testosterone is associated with CHD.</p><p></p><p>Your T/E2 ratio by the study method is 4.23, worse than the CHD average. Your E2/T ratio is 0.24%. Either way your ratio is skewed towards testosterone, possibly increasing your risk. You might check the same lab markers they used, and worry less if they are ok.</p><p></p><p>Full study attached for your viewing pleasure.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 260898, member: 38109"] Personally I prefer the E2/T ratio, either by weight or molar concentration. In any case, this study appears to use T in ng/dL divided by (10 times E2 in pg/mL). No explanation why—perhaps just to make nice numbers. Controls had T = 611.42 and E2 = 36.35. CHD cases had T = 522.44 and E2 = 20.73. I assume the ratios were calculated before averaging, so the ratio of the averages is not equal to the average of the ratios. That is, in the CHD group 522.44 / 10 / 20.73 = 2.52, which is different from the stated ratio of 3.28. Looking at their results as E2/T, the control is 0.59%, while the CHD group is 0.30%. I've been giving a normal range for E2/T as something like 0.3-0.6%, so their control does seem to be on the high side. It's probably best not to focus too hard on the absolute numbers. Instead the message is that less estradiol relative to testosterone is associated with CHD. Your T/E2 ratio by the study method is 4.23, worse than the CHD average. Your E2/T ratio is 0.24%. Either way your ratio is skewed towards testosterone, possibly increasing your risk. You might check the same lab markers they used, and worry less if they are ok. Full study attached for your viewing pleasure. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Imbalance of testosterone/estradiol promotes male CHD development
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