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The Hang Out - Where Everything Goes!
Im a COVID ICU nurse. Ask me (almost) anything.
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<blockquote data-quote="Matthew1975" data-source="post: 196320" data-attributes="member: 16306"><p>Figured I'd cite sources in the beginning rather than the end of what I write.</p><p></p><p>[URL unfurl="true"]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1232869/[/URL]</p><p></p><p>[URL unfurl="true"]https://www.sciencedirect.com/science/article/pii/S0002934320306732[/URL]</p><p></p><p>[URL unfurl="true"]https://www.ijidonline.com/article/S1201-9712(20)30534-8/fulltext[/URL]</p><p></p><p>[URL unfurl="true"]https://www.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.001250[/URL]</p><p></p><p></p><p>As an RN working in NJ, who first encountered Covid in the ER, then was pulled back to ICU for three months (have 10 years Trauma/Neuro ICU), I'll add to the conversation, in no particular order.</p><p></p><p>- The term "case" is misleading: it does not mean the person has any symptoms, it does not mean the person has an active infection. All it means is that the swab managed to get enough pieces of coronavirus RNA that when put in the machine and cycled 35-40 times, it shows coronavirus is present. Look up "cycle threshold" issues, and you'll see why this is a problem. If I swab a countertop that has bits of Covid RNA on it, I can get a positive result, doesn't mean the counter is infected. </p><p></p><p>- Swabs are not only highly inaccurate (leaning towards false positives), but so much depends on technique and cooperation of the patient, as well as possible stage of the infection. After 5-7 days, the infection is not as easily isolated in the nasopharynx, so someone could swab negative, but have multiple symptoms as a well as a very concerning chest x-ray or CT.</p><p></p><p>- For some time, yes, there were refrigerated trailers at hospitals, not because morgues and funeral homes were "overwhelmed" due to volume, but because the bodies were considered biohazards. There was not enough knowledge regarding how the virus is transmitted, nor enough PPE and precautions in place for those who normally care for the deceased. There were instances were funeral homes simply would not accept the remains for a period of time, and most hospital morgues are not that large.</p><p></p><p>- The Federal government was the only governmental agency, specifically DOD, who was prepared to help. The state of NJ was not, from Trenton down to the local level. We were initially asked to reuse disposable N95 masks for a week, which are only rated to be worn and effective for 8 hours. Fortunately, our ER Chief Attending was able to get all staff P100 respirators with replaceable filters.</p><p></p><p>- There is plenty of evidence that hydroxychloroquine, along with zinc and azithromycin or doxycycline, are effective in <em><strong>early</strong></em> Covid infections. HCQ serves as a zinc ionophore, helping push zinc into the RNA of the virus, disrupting replication. HCQ is not unique in this, quercetin and EgCg, from green tea, are also zinc ionophores. This combo, or something like ivermectin, must be taken BEFORE the ferritin release and cytokine storm.</p><p></p><p>- The reason this combo doesn't help someone in an advanced state of infection is that while the virus resembles ARDS, it is NOT ARDS. Much of the damage results from the cytokine storm, but also from the patient's red blood cells releasing large amounts of ferritin (iron). The iron causes oxidative and physical damage to the lungs and other organs, which is why someone with moderate and above Covid, their chest x-ray or chest CT shows bilateral ground glass opacities. This is a hallmark of Covid and is a result of the x-rays scattering due to the high ferritin (iron) levels.</p><p></p><p>The best way to understand this is if you get bitten by a rattlesnake, you cannot wait until your leg is black and about to fall off to receive antivenom, as by then, the damage is done.</p><p></p><p>- It is not easy to contract Covid, it definitely requires some level of sustained interaction with someone who has the virus and is infectious. Knowing what I know now, I would have absolutely no problem going to the grocery store without a mask.</p><p></p><p>- Furthermore, we (the staff of the ER), are positive we had Covid patients starting in mid-late December 2019. We kept getting patient after patient presenting with flu-like symptoms or respiratory complaints, and no one was testing positive for the flu. None of us working in the ER got sick. I helped intubate a patient who in the span of 20 minutes, went from short of breath but talking, to struggling to breathe and unable to speak, to being emergently intubated. I had on no mask (very early in the pandemic), and none of us in the room got sick from this patient, who unfortunately died the next day.</p><p></p><p>- I did contract an extremely mild case of Covid while working the ICU where the entire unit was filled with virus. There was some loss of smell and taste for about 3 days, some scattered, intermittent aches that would come and go, but the worst part was the fatigue. I had no energy for about 10-11 days. For those wondering, I have O+ blood, and I also have an excellent immune system, fortified with researched supplementation. After the first few days, I could have gone into work if they needed me, but the fatigue would have really slowed me down.</p><p></p><p>- I realized I had Covid when I developed a dry cough. People who take ACE inhibitors for hypertension often experience the side effect of a dry cough. Since Covid targets the body's ACE receptors, just like an ACE inhibitor, I correctly surmised that I must have Covid. (told the ER docs my rationale and, in a sickening example of self-praise, they were impressed with my logic, as they hadn't considered that)</p><p></p><p>- A mask will not filter out virus particles. Yes, it will catch droplets if someone coughs or sneezes, but the vast majority of people do not want to sneeze in their mask, so generally it comes off then they sneeze. I had to sneeze in a Covid patient's ICU room while wearing my Moldex P100 respirator...what an unpleasant mess that was.</p><p></p><p>- Unless you have been fit-tested for a respirator, don't bother with N95's. Without proper fit testing, you have no idea as to the effectiveness. We are overdoing the precautions as it is...like if you stop to get coffee or a drink and they put the drink in some sort of box and pass it to you.</p><p></p><p>- Anything rated at KN95 is not made in the USA. FDA has tested them, and many are not as effective as a standard, disposable surgical mask. There are also a lot of fake 3M N95's, made in China, which are far less protective than the real product.</p><p></p><p>- Remdesivir...nah.</p><p></p><p>- This virus has been made far too political by people who put politics before truth. A perfect example is hydroxychloroquine. Not only did people immediately deride the medication because they didn't like the person talking about it, the medication was immediately demonized. "It's not safe, it has so many side effects, it's more dangerous than Covid!" Hydroxychloroquine is taken by millions of people worldwide on a daily basis, and this has held true for decades. In many nations, hydroxychloroquine is sold without a prescription. So a drug safely used by millions of people on a daily basis is suddenly dangerous? Think about it.</p><p></p><p>- Looking at actual evidence, this virus has the hallmarks of "gain of function" studies, not a virus suddenly making the leap from a Horseshoe nose bat (that wasn't even sold at the Wuhan wet market, and isn't found within 500 miles of Wuhan, except at the BSL-4 at the Virology Institute).</p></blockquote><p></p>
[QUOTE="Matthew1975, post: 196320, member: 16306"] Figured I'd cite sources in the beginning rather than the end of what I write. [URL unfurl="true"]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1232869/[/URL] [URL unfurl="true"]https://www.sciencedirect.com/science/article/pii/S0002934320306732[/URL] [URL unfurl="true"]https://www.ijidonline.com/article/S1201-9712(20)30534-8/fulltext[/URL] [URL unfurl="true"]https://www.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.001250[/URL] As an RN working in NJ, who first encountered Covid in the ER, then was pulled back to ICU for three months (have 10 years Trauma/Neuro ICU), I'll add to the conversation, in no particular order. - The term "case" is misleading: it does not mean the person has any symptoms, it does not mean the person has an active infection. All it means is that the swab managed to get enough pieces of coronavirus RNA that when put in the machine and cycled 35-40 times, it shows coronavirus is present. Look up "cycle threshold" issues, and you'll see why this is a problem. If I swab a countertop that has bits of Covid RNA on it, I can get a positive result, doesn't mean the counter is infected. - Swabs are not only highly inaccurate (leaning towards false positives), but so much depends on technique and cooperation of the patient, as well as possible stage of the infection. After 5-7 days, the infection is not as easily isolated in the nasopharynx, so someone could swab negative, but have multiple symptoms as a well as a very concerning chest x-ray or CT. - For some time, yes, there were refrigerated trailers at hospitals, not because morgues and funeral homes were "overwhelmed" due to volume, but because the bodies were considered biohazards. There was not enough knowledge regarding how the virus is transmitted, nor enough PPE and precautions in place for those who normally care for the deceased. There were instances were funeral homes simply would not accept the remains for a period of time, and most hospital morgues are not that large. - The Federal government was the only governmental agency, specifically DOD, who was prepared to help. The state of NJ was not, from Trenton down to the local level. We were initially asked to reuse disposable N95 masks for a week, which are only rated to be worn and effective for 8 hours. Fortunately, our ER Chief Attending was able to get all staff P100 respirators with replaceable filters. - There is plenty of evidence that hydroxychloroquine, along with zinc and azithromycin or doxycycline, are effective in [I][B]early[/B][/I] Covid infections. HCQ serves as a zinc ionophore, helping push zinc into the RNA of the virus, disrupting replication. HCQ is not unique in this, quercetin and EgCg, from green tea, are also zinc ionophores. This combo, or something like ivermectin, must be taken BEFORE the ferritin release and cytokine storm. - The reason this combo doesn't help someone in an advanced state of infection is that while the virus resembles ARDS, it is NOT ARDS. Much of the damage results from the cytokine storm, but also from the patient's red blood cells releasing large amounts of ferritin (iron). The iron causes oxidative and physical damage to the lungs and other organs, which is why someone with moderate and above Covid, their chest x-ray or chest CT shows bilateral ground glass opacities. This is a hallmark of Covid and is a result of the x-rays scattering due to the high ferritin (iron) levels. The best way to understand this is if you get bitten by a rattlesnake, you cannot wait until your leg is black and about to fall off to receive antivenom, as by then, the damage is done. - It is not easy to contract Covid, it definitely requires some level of sustained interaction with someone who has the virus and is infectious. Knowing what I know now, I would have absolutely no problem going to the grocery store without a mask. - Furthermore, we (the staff of the ER), are positive we had Covid patients starting in mid-late December 2019. We kept getting patient after patient presenting with flu-like symptoms or respiratory complaints, and no one was testing positive for the flu. None of us working in the ER got sick. I helped intubate a patient who in the span of 20 minutes, went from short of breath but talking, to struggling to breathe and unable to speak, to being emergently intubated. I had on no mask (very early in the pandemic), and none of us in the room got sick from this patient, who unfortunately died the next day. - I did contract an extremely mild case of Covid while working the ICU where the entire unit was filled with virus. There was some loss of smell and taste for about 3 days, some scattered, intermittent aches that would come and go, but the worst part was the fatigue. I had no energy for about 10-11 days. For those wondering, I have O+ blood, and I also have an excellent immune system, fortified with researched supplementation. After the first few days, I could have gone into work if they needed me, but the fatigue would have really slowed me down. - I realized I had Covid when I developed a dry cough. People who take ACE inhibitors for hypertension often experience the side effect of a dry cough. Since Covid targets the body's ACE receptors, just like an ACE inhibitor, I correctly surmised that I must have Covid. (told the ER docs my rationale and, in a sickening example of self-praise, they were impressed with my logic, as they hadn't considered that) - A mask will not filter out virus particles. Yes, it will catch droplets if someone coughs or sneezes, but the vast majority of people do not want to sneeze in their mask, so generally it comes off then they sneeze. I had to sneeze in a Covid patient's ICU room while wearing my Moldex P100 respirator...what an unpleasant mess that was. - Unless you have been fit-tested for a respirator, don't bother with N95's. Without proper fit testing, you have no idea as to the effectiveness. We are overdoing the precautions as it is...like if you stop to get coffee or a drink and they put the drink in some sort of box and pass it to you. - Anything rated at KN95 is not made in the USA. FDA has tested them, and many are not as effective as a standard, disposable surgical mask. There are also a lot of fake 3M N95's, made in China, which are far less protective than the real product. - Remdesivir...nah. - This virus has been made far too political by people who put politics before truth. A perfect example is hydroxychloroquine. Not only did people immediately deride the medication because they didn't like the person talking about it, the medication was immediately demonized. "It's not safe, it has so many side effects, it's more dangerous than Covid!" Hydroxychloroquine is taken by millions of people worldwide on a daily basis, and this has held true for decades. In many nations, hydroxychloroquine is sold without a prescription. So a drug safely used by millions of people on a daily basis is suddenly dangerous? Think about it. - Looking at actual evidence, this virus has the hallmarks of "gain of function" studies, not a virus suddenly making the leap from a Horseshoe nose bat (that wasn't even sold at the Wuhan wet market, and isn't found within 500 miles of Wuhan, except at the BSL-4 at the Virology Institute). [/QUOTE]
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The Hang Out - Where Everything Goes!
Im a COVID ICU nurse. Ask me (almost) anything.
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