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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
IGF-1 came back very elevated. I'm panicking. How concerned should I be?
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<blockquote data-quote="eyeheartny" data-source="post: 119351" data-attributes="member: 18882"><p>Thanks Mark. I think the distinction Vince missed is between a pituitary adenoma and acromegaly. I have no other symptoms of pituitary disease (normal prolactin, expected low FSH/LH being on TRT, etc) and the only abnormal result is the elevated IGF-1. So the labs raise suspicion of a pituitary adenoma producing excess growth hormone, which would be signaling the liver to produce IGF-1. But since I did not meet the criteria for acromegaly, we can assume that there isn't a pituitary tumor that's producing growth hormone. Vince is partially right that I may still have a pituitary tumor, but it isn't one that's producing GH, because the OGTT demonstrated that my body does in fact suppress GH levels in response to the glucose load. I think Vince is just a little confused on terms and concepts, but you're absolutely right that there are other ways to diagnose acromegaly. </p><p></p><p>Anyhow, I have an MRI in about an hour that will be definitive here, but my endocrinologist described the OGTT results as "reassuring," even though we don't know why I present with elevated IGF-1.</p></blockquote><p></p>
[QUOTE="eyeheartny, post: 119351, member: 18882"] Thanks Mark. I think the distinction Vince missed is between a pituitary adenoma and acromegaly. I have no other symptoms of pituitary disease (normal prolactin, expected low FSH/LH being on TRT, etc) and the only abnormal result is the elevated IGF-1. So the labs raise suspicion of a pituitary adenoma producing excess growth hormone, which would be signaling the liver to produce IGF-1. But since I did not meet the criteria for acromegaly, we can assume that there isn't a pituitary tumor that's producing growth hormone. Vince is partially right that I may still have a pituitary tumor, but it isn't one that's producing GH, because the OGTT demonstrated that my body does in fact suppress GH levels in response to the glucose load. I think Vince is just a little confused on terms and concepts, but you're absolutely right that there are other ways to diagnose acromegaly. Anyhow, I have an MRI in about an hour that will be definitive here, but my endocrinologist described the OGTT results as "reassuring," even though we don't know why I present with elevated IGF-1. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
IGF-1 came back very elevated. I'm panicking. How concerned should I be?
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