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Thyroid, Pregnenolone, Progesterone, DHEA, etc
Thyroid, DHEA, Pregnenolone, Progesterone, etc
IFG-1, IGF-1 signaling, good or bad?
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<blockquote data-quote="DragonBits" data-source="post: 129546" data-attributes="member: 18023"><p>I am a little confused about IGF-1 issues.</p><p></p><p>There is a thread suggestion that higher IGF-1 levels are good for your health, and drugs are sold to stimulate GF/IGF-1 production.</p><p></p><p>On the other hand, Metformin is a drug that is often recommended for glucose control as well as its anti-aging properties. A miracle drug.</p><p></p><p>Part of what metformin does is reduce IGF-1 Signaling.</p><p></p><p>I am not sure what IGF-signaling really means, and if you increase IGF-1 levels, do you get more signaling which you want to reduce? Does lowering IGF-1 levels also lower signalling? Can you raise GH but lower IGF-1 and is that better?</p><p></p><p>Or is IGF-1 one of those J curve hormones where the sweet spot is in the middle?</p><p></p><p>Does anyone have an insight into these issues?</p></blockquote><p></p>
[QUOTE="DragonBits, post: 129546, member: 18023"] I am a little confused about IGF-1 issues. There is a thread suggestion that higher IGF-1 levels are good for your health, and drugs are sold to stimulate GF/IGF-1 production. On the other hand, Metformin is a drug that is often recommended for glucose control as well as its anti-aging properties. A miracle drug. Part of what metformin does is reduce IGF-1 Signaling. I am not sure what IGF-signaling really means, and if you increase IGF-1 levels, do you get more signaling which you want to reduce? Does lowering IGF-1 levels also lower signalling? Can you raise GH but lower IGF-1 and is that better? Or is IGF-1 one of those J curve hormones where the sweet spot is in the middle? Does anyone have an insight into these issues? [/QUOTE]
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Thyroid, Pregnenolone, Progesterone, DHEA, etc
Thyroid, DHEA, Pregnenolone, Progesterone, etc
IFG-1, IGF-1 signaling, good or bad?
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