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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
I think neglected Total Testosterone focusing too much on free T...
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<blockquote data-quote="Cataceous" data-source="post: 178209" data-attributes="member: 38109"><p>In the absence of better knowledge I figure it's safest to target mid-range. Most of us don't know what our optimal youthful levels for hormones were, so I look at what the average healthy young guy might have. This would be roughly: TT: 600-700 ng/dL, E2: 30 pg/mL, SHBG: 30 nMol/L. This is putting calculated free estradiol at about 0.7-0.8 pg/mL, which is indeed mid-range on the reference scale.</p><p></p><p>As you note, this may or may not apply to guys with low SHBG. I haven't seen enough data to say if there's some systematic difference, such as needing a lower estradiol target, or needing to force the free hormone ratios to more normal values.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 178209, member: 38109"] In the absence of better knowledge I figure it's safest to target mid-range. Most of us don't know what our optimal youthful levels for hormones were, so I look at what the average healthy young guy might have. This would be roughly: TT: 600-700 ng/dL, E2: 30 pg/mL, SHBG: 30 nMol/L. This is putting calculated free estradiol at about 0.7-0.8 pg/mL, which is indeed mid-range on the reference scale. As you note, this may or may not apply to guys with low SHBG. I haven't seen enough data to say if there's some systematic difference, such as needing a lower estradiol target, or needing to force the free hormone ratios to more normal values. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
I think neglected Total Testosterone focusing too much on free T...
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