I feel best one 1 injection 100mg a week

[franksepe]

Ive been on TRT 8 years now. I found that I feel best on 100mg a week. Strong erections and good quality orgasms. For the past 3-4 years I have been splitting injections up in varying amounts 100mg/110/120/130/140mg split into twice a week.. Nothing ever works as good for me. What is the explanation for this? On blood work my estrogen drops from splitting it up and total & free Testosterone drops which is to be expected. The reason for splitting it up is due to the internet. But now I am just going back to what worked the best. I am not going to post 8 years of blood work it will take to long to sift through it and remember what routine I was on during that time period.

 

[SilverSurfer]

The best protocol is the one you feel the best using IMO. I feel no different if I dose once every other week, every week, or twice a week. I feel the same. Many guys, probably the vast majority, are fine with an injection once every other week, something you would think is a disastrous protocol around these parts. The Nth percentile seek forums out like this that a standard protocol doesn’t work well for, or are seeking to dial in their protocols, and that’s ok.

 

[Sean Mosher]

Definitely no need to over-think.
You found what works.
Stick with it.
It would be interesting for us to see your bloodwork on the protocol you feel the best.
Congrats!

 

[S1W]

Ive been on TRT 8 years now. I found that I feel best on 100mg a week. Strong erections and good quality orgasms. For the past 3-4 years I have been splitting injections up in varying amounts 100mg/110/120/130/140mg split into twice a week.. Nothing ever works as good for me. What is the explanation for this? On blood work my estrogen drops from splitting it up and total & free Testosterone drops which is to be expected. The reason for splitting it up is due to the internet. But now I am just going back to what worked the best. I am not going to post 8 years of blood work it will take to long to sift through it and remember what routine I was on during that time period.

You're not the first person I've heard say that here. Thanks for sharing.

Of course it would be unreasonable to post 8 years of blood work, but could you perhaps share your SHBG?

I ask because although I have seen high SHBG guys say they benefit from more frequent injections (which most would say are unnecessary for high SHBG) I have not yet heard from low SHBG guys saying they do better on 1x/week or less frequent protocols.

 

[Vince]

Sometimes I think that may be the number one protocol for most men. "1 injection 100mg week"

 

[Pringle]

I felt just as good on once weekly as I do now on daily shots. The only reason I changed to E3.5D and then to daily was I needed an AI eliminate high E2 sides.....If I could have controlled E2 on weekly dosages, without an AI, I would still be doing weekly injections.

 

[S1W]

I felt just as good on once weekly as I do now on daily shots. The only reason I changed to E3.5D and then to daily was I needed an AI eliminate high E2 sides.....If I could have controlled E2 on weekly dosages, without an AI, I would still be doing weekly injections.

Respectfully, unless I misunderstood something, that doesn't really make sense. If you had high E2 sides on 1x/week that you felt needed to be controlled with an AI, and now on dailies you do not have those issues, that would seem to indicate that the daily protocol actually is working out better for you.

Or are you saying that you felt just as good on the 1x/week with AI as you do now on daily with no AI?

 

[sh1973]

I’ve tried splitting the dose several times and feel much better doing once weekly. Been on trt over nine years.

 

[franksepe]

Thanks guys. And I dont have any recent SHBG tests to give you. I rarely get that tested when I go now. It costs me money because my insurance does not cover that particular test.

 

[Pringle]

Respectfully, unless I misunderstood something, that doesn't really make sense. If you had high E2 sides on 1x/week that you felt needed to be controlled with an AI, and now on dailies you do not have those issues, that would seem to indicate that the daily protocol actually is working out better for you.

Or are you saying that you felt just as good on the 1x/week with AI as you do now on daily with no AI?

Your later interpretation is Correct. When I was on daily injections my E2 would spike after the injection and I had to dose an AI to control E2 symptoms to feel good overall. Now I feel basically the same on daily without having to take the AI.

 

[equel]

Do u have any idea of your SHBG levels OP?

 

[franksepe]

Do u have any idea of your SHBG levels OP?

No.

 

[James]

The reason for splitting it up is due to the internet.

I'd guess you're likely a mid/high SHBG guy if the once weekly protocol works best. The reason for splitting it up is because it's a valid injection schedule for some, like me, who have low SHBG. I agree with Vince that the 100 mg once weekly seems is popular with most guys. If I were to ever to go back to a once weekly schedule, that would likely be my choice.

 

[tropicaldaze1950]

The discussion of a weekly 100 mg injection vs split dose 2xweekly, EOD, vs ED, vs IM vs sub q is similar to research I've done on the best form of B12. What I've found in reading many abstracts is that the first formulation, cyancobalamin, used since after WW2, is effective in injectable form, sublingual, oral and even as a paste applied in the nose. TRT isn't as straight forward and there are many variables that do, or can, impact a individual's response to a protocol, but simplicity is elegant. When we start trying to micro manage, that could be the beginning of problems. I'm ditching my EOD, sub q for once weekly 100 mg, IM.

 

[Gianluca]

Ive been on TRT 8 years now. I found that I feel best on 100mg a week. Strong erections and good quality orgasms. For the past 3-4 years I have been splitting injections up in varying amounts 100mg/110/120/130/140mg split into twice a week.. Nothing ever works as good for me. What is the explanation for this? On blood work my estrogen drops from splitting it up and total & free Testosterone drops which is to be expected. The reason for splitting it up is due to the internet. But now I am just going back to what worked the best. I am not going to post 8 years of blood work it will take to long to sift through it and remember what routine I was on during that time period.

interesting, I have started at 1 injection per week then moved to 2 then 3 then everyday, I have to say I don't remember the 1 x per week period, but going from 2 x week to 3 x week made no much difference, and the only thing I noticed on every day is that I felt more "natural" when the other times I would feel on something. And to mention I have low SHBG

 

[Gianluca]

No.

I would be very curios to see what your SHBG is