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Message: <blockquote data-quote="Vitamin_C" data-source="post: 85196" data-attributes="member: 12373">I understand, but to be the first person this has happened to in medical literature would require you to take large doses of ethinylestradiol to see if you respond but you are unwilling to do so.  There is also no known pharmacological means in which Arimidex would do this, and this is a VERY studied drug in literature.  Also, why would increasing your E2 make your insensitivity symptoms worse?  Also, many dudes feel like ass on Clomid, I just heard Dr. Rand McClain mention this.Do you have any abnormal labs you could post that shows estrogen is not physiologically working in your body?  There should be clues in the labwork if E2 is not doing its thing.</blockquote>

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