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When I crashed my E2? All my tests have been sensitive, I was at 5 at the lowest in August, a month later I was at 9, a month later I was at 26 and my latest one I was at 21. Are you theorizing you  need to be at zero for a while in order for this to happen?  My current symptoms are anxiety and joint popping, libido is good, erections are good when I'm not anxious,  but I didn't start getting bad anxiety till I started reading about the "permanent" theoretical E2 stuff which really ramped up my anxiety so I started researching through pubmed at my university (I am a doctoral student) and I just couldn't find good data to support this.  I also exhaustively searched the web on bodybuilding sites where many dudes have crashed their E2 on accident or purposely lower their E2 for bodybuilding shows and couldn't find any feedback that supports this either, but you can find a lot on PFS.  A lot of anxiety symptoms will mirror low E2 symptoms as well, same with hypoadrenal.