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Testosterone Replacement, Low T, HCG, & Beyond
Clomid for PCT, fertility or low T
HPTA restart need help
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<blockquote data-quote="madman" data-source="post: 124307" data-attributes="member: 13851"><p>Before starting pct one needs to wait for the testosterone to clear their system.</p><p></p><p>Nebido (Testosterone Undecanoate)</p><p></p><p>Ester/dosage will effect how long it takes for the testosterone to clear your system after your last injection.</p><p></p><p>The undecanoate ester is long acting and doses used when injecting Nebido are high so it could take up to 3 months to clear your system.</p><p></p><p></p><p><strong>Intramuscular Testosterone Undecanoate: Pharmacokinetic Aspects of a Novel Testosterone Formulation during Long-Term Treatment of Men with Hypogonadism <span style="color: rgb(184, 49, 47)">(posted pdf below)</span></strong> </p><p></p><p>Clinical long-term experience up to 120-weeks was published in 2004 (<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686335/#b38-cia-2-577" target="_blank">Schubert et al 2004</a>). Twenty-six hypogonadal patients received TU (1000 mg TU/4mL) in a first stage of the study in weeks 0, 6, 16, 26, and 36, followed by an additional stage of up to 120-weeks with injections every 12-weeks. The supranormal peak concentrations of total and free T occurred 2-weeks after the first injection, then a decrease to within the physiological range was observed.<span style="color: rgb(184, 49, 47)">At the end of the study, during washout period, serum T levels declined to the low pre-treatment levels 14-weeks after the final injection.</span></p><p></p><p>In your case you stated for the last few months you are now injecting 4ml (1000mg) every 4 weeks which is much sooner than the standard protocol.</p><p></p><p></p><p></p><p>Below is from Nelson's post in another thread regarding PCT meds/doses</p><p></p><p><strong>The protocol for HPTA normalization contains (edited on Dec 2017): </strong></p><p></p><p><strong>First 15 days:</strong></p><p></p><p>HCG 1,000-2,000 IU (subcutaneous) every 3 days;</p><p>Clomiphene citrate 25-50 mg orally once a day; and</p><p>Tamoxifen 20 mg orally once a day.</p><p></p><p>A satisfactory testosterone level on day 15, typically 350 ng/mL or greater, is followed by the oral medications (no HCG) for an additional 15 days (25 mg per day clomiphene would be sufficient in most cases).</p><p></p><p>This protocol has not been tested in many patients but has shown good results in restoring HPTA in a month. I know that this sounds like a long time but without treatment, the body's restoration process would take about the same length of time that somebody was using androgens. In some, HPGA function and testosterone production never returns to normal.</p></blockquote><p></p>
[QUOTE="madman, post: 124307, member: 13851"] Before starting pct one needs to wait for the testosterone to clear their system. Nebido (Testosterone Undecanoate) Ester/dosage will effect how long it takes for the testosterone to clear your system after your last injection. The undecanoate ester is long acting and doses used when injecting Nebido are high so it could take up to 3 months to clear your system. [B]Intramuscular Testosterone Undecanoate: Pharmacokinetic Aspects of a Novel Testosterone Formulation during Long-Term Treatment of Men with Hypogonadism [COLOR=rgb(184, 49, 47)](posted pdf below)[/COLOR][/B] Clinical long-term experience up to 120-weeks was published in 2004 ([URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686335/#b38-cia-2-577']Schubert et al 2004[/URL]). Twenty-six hypogonadal patients received TU (1000 mg TU/4mL) in a first stage of the study in weeks 0, 6, 16, 26, and 36, followed by an additional stage of up to 120-weeks with injections every 12-weeks. The supranormal peak concentrations of total and free T occurred 2-weeks after the first injection, then a decrease to within the physiological range was observed.[COLOR=rgb(184, 49, 47)]At the end of the study, during washout period, serum T levels declined to the low pre-treatment levels 14-weeks after the final injection.[/COLOR] In your case you stated for the last few months you are now injecting 4ml (1000mg) every 4 weeks which is much sooner than the standard protocol. Below is from Nelson's post in another thread regarding PCT meds/doses [B]The protocol for HPTA normalization contains (edited on Dec 2017): [/B] [B]First 15 days:[/B] HCG 1,000-2,000 IU (subcutaneous) every 3 days; Clomiphene citrate 25-50 mg orally once a day; and Tamoxifen 20 mg orally once a day. A satisfactory testosterone level on day 15, typically 350 ng/mL or greater, is followed by the oral medications (no HCG) for an additional 15 days (25 mg per day clomiphene would be sufficient in most cases). This protocol has not been tested in many patients but has shown good results in restoring HPTA in a month. I know that this sounds like a long time but without treatment, the body's restoration process would take about the same length of time that somebody was using androgens. In some, HPGA function and testosterone production never returns to normal. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Clomid for PCT, fertility or low T
HPTA restart need help
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