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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
How to Predict Estradiol and DHT at Different Testosterone Doses
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<blockquote data-quote="Jerajera" data-source="post: 228702" data-attributes="member: 40995"><p>What am I missing here?</p><p></p><p>If you take a TT of 1,000ng/dL, the formula for young men gives an E2 of approximately 33pg/mL, while the formula for older men gives an E2 of ~55pg/mL, almost double that of young men.</p><p></p><p>Has anyone actually run those numbers and compared them?</p><p></p><p>To me this could be evidence that the much higher ratio of E2 to TT is a significant reason older men don't feel as good as younger men. Actually if you look at the table in the OP, the older men's ratio of E2 to TT is double that of younger men's, 0.8 vs 0.4.</p><p></p><p>An obvious culprit could be the significant bodyfat percentage difference between old and young men. But that assumes a specific causal relationship in the direction of higher BF -> higher E2.</p><p></p><p>I'm not sure that's completely accurate. What if it was higher E2 -> higher BF -> higher E2 -> ...</p><p></p><p>I don't know about you but when I was 20yo I didn't have to work out or watch my diet to be lean. Now I have to work out like an animal to stay around 12% BF even on TRT.</p><p></p><p>I'm not sure I understand how the message here is "don't worry about E2". To me, the message looks more like "younger men have half the E2 of their older counterparts at equivalent TT levels, and that's probably the reason they feel a million times better on average"</p></blockquote><p></p>
[QUOTE="Jerajera, post: 228702, member: 40995"] What am I missing here? If you take a TT of 1,000ng/dL, the formula for young men gives an E2 of approximately 33pg/mL, while the formula for older men gives an E2 of ~55pg/mL, almost double that of young men. Has anyone actually run those numbers and compared them? To me this could be evidence that the much higher ratio of E2 to TT is a significant reason older men don't feel as good as younger men. Actually if you look at the table in the OP, the older men's ratio of E2 to TT is double that of younger men's, 0.8 vs 0.4. An obvious culprit could be the significant bodyfat percentage difference between old and young men. But that assumes a specific causal relationship in the direction of higher BF -> higher E2. I'm not sure that's completely accurate. What if it was higher E2 -> higher BF -> higher E2 -> ... I don't know about you but when I was 20yo I didn't have to work out or watch my diet to be lean. Now I have to work out like an animal to stay around 12% BF even on TRT. I'm not sure I understand how the message here is "don't worry about E2". To me, the message looks more like "younger men have half the E2 of their older counterparts at equivalent TT levels, and that's probably the reason they feel a million times better on average" [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
How to Predict Estradiol and DHT at Different Testosterone Doses
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