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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
How to improve penile sensitivity?
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<blockquote data-quote="Cataceous" data-source="post: 242293" data-attributes="member: 38109"><p>These are borderline numbers. Vermeulen calculated free testosterone is near the bottom of the normal range. Some guys will have trouble here, others won't. At this point I wouldn't worry too much about it—though if you want you could retreat to TRT lite, by which I'm referring to fast acting testosterone products, such as nasal gel or troches. These cause less hormonal disruption and fewer side effects than conventional TRT.</p><p></p><p></p><p>A total testosterone target of 800 ng/dL would be appropriate if your SHBG is still 45 nMol/L. However, it's likely that SHBG has declined due to TRT. Instead, shoot for a Vermeulen calculated free testosterone of 15 ng/dL or a little higher. This is around average for healthy young guys. I've argued that average is a good place to be when we don't know what's optimal. The reasoning is that nature has already selected average as the best place to be for reproductive success—and historically reproductive success correlates with overall success in life.</p><p></p><p>This could seem counterintuitive, because we're used to thinking that higher extremes are better, as in test results and sports scores. But biology is a little different. Consider physical attractiveness. You might think that somebody with remarkable beauty would have more extreme features. But it turns out the opposite is true. The ones judged most attractive tend to have overall features closer to average. More extreme features, such as a face that's too wide or too narrow, are innately considered red flags for dubious genetic fitness. Thus extremes in biology are generally not a good thing. This applies to hormones of course, where high or low levels are often associated with higher mortality.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 242293, member: 38109"] These are borderline numbers. Vermeulen calculated free testosterone is near the bottom of the normal range. Some guys will have trouble here, others won't. At this point I wouldn't worry too much about it—though if you want you could retreat to TRT lite, by which I'm referring to fast acting testosterone products, such as nasal gel or troches. These cause less hormonal disruption and fewer side effects than conventional TRT. A total testosterone target of 800 ng/dL would be appropriate if your SHBG is still 45 nMol/L. However, it's likely that SHBG has declined due to TRT. Instead, shoot for a Vermeulen calculated free testosterone of 15 ng/dL or a little higher. This is around average for healthy young guys. I've argued that average is a good place to be when we don't know what's optimal. The reasoning is that nature has already selected average as the best place to be for reproductive success—and historically reproductive success correlates with overall success in life. This could seem counterintuitive, because we're used to thinking that higher extremes are better, as in test results and sports scores. But biology is a little different. Consider physical attractiveness. You might think that somebody with remarkable beauty would have more extreme features. But it turns out the opposite is true. The ones judged most attractive tend to have overall features closer to average. More extreme features, such as a face that's too wide or too narrow, are innately considered red flags for dubious genetic fitness. Thus extremes in biology are generally not a good thing. This applies to hormones of course, where high or low levels are often associated with higher mortality. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
How to improve penile sensitivity?
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