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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
How to co relate RIA and equilibrium dialysis reports
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<blockquote data-quote="madman" data-source="post: 278993" data-attributes="member: 13851"><p>You would need to have your FT tested using an accurate assay such as the gold standard Equilibrium Dialysis or Ultrafiltration especially in cases of altered SHBG to know where it truly sits.</p><p></p><p>No on should be using/relying upon the direct immunoassay especially in cases of altered SHBG.</p><p></p><p>Seeing as you do not have access to the most accurate assays (ED/UF) then you would need to use/rely upon the linear law-of-mass action cFTV which is available online for free.</p><p></p><p>Keep in mind as of now cFTV tends to overestimate when compared to a standardized gold standard ED assay.</p><p></p><p>Also keep in mind that Quests /Labcorps let alone any of the other labs Equilibrium Dialysis or Equilibrium Ultrafiltration assays in the US or any other country are not standardized!</p><p></p><p>Top it of that there is no harmonized reference range to boot!</p><p></p><p>In an ideal situation TT and SHBG should be tested using the most accurate assays but you can nitpick when it comes to low vs high TT let alone assays currently available for SHBG.</p><p></p><p>I will put it to you like this you can be rest assured that if you have low or normal SHBG and you are hitting a high-end trough TT then your trough FT would be high/very high!</p></blockquote><p></p>
[QUOTE="madman, post: 278993, member: 13851"] You would need to have your FT tested using an accurate assay such as the gold standard Equilibrium Dialysis or Ultrafiltration especially in cases of altered SHBG to know where it truly sits. No on should be using/relying upon the direct immunoassay especially in cases of altered SHBG. Seeing as you do not have access to the most accurate assays (ED/UF) then you would need to use/rely upon the linear law-of-mass action cFTV which is available online for free. Keep in mind as of now cFTV tends to overestimate when compared to a standardized gold standard ED assay. Also keep in mind that Quests /Labcorps let alone any of the other labs Equilibrium Dialysis or Equilibrium Ultrafiltration assays in the US or any other country are not standardized! Top it of that there is no harmonized reference range to boot! In an ideal situation TT and SHBG should be tested using the most accurate assays but you can nitpick when it comes to low vs high TT let alone assays currently available for SHBG. I will put it to you like this you can be rest assured that if you have low or normal SHBG and you are hitting a high-end trough TT then your trough FT would be high/very high! [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
How to co relate RIA and equilibrium dialysis reports
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