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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
How much testosterone is converted to estradiol?
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<blockquote data-quote="johndoesmith" data-source="post: 53461" data-attributes="member: 13404"><p>Ha, thank you. I enjoy researching this topic, most of my questions are lost as thoughts or questions come to me when I'm driving and I ALWAYS tell myself "I'll remember that for later!" and it never happens. </p><p></p><p>I do recall discussing with you the possibility of Test bound to SHBG unbinding, therefore could aromatize. I imagine that is probably something no one honestly knows at this point in time.</p><p></p><p>I digress, I have noticed a bit of a pattern myself with my free test and E2 readings, E2 is always about 2-3pg/ml higher than my free test. They follow very closely. </p><p></p><p>I imagine that individual aromatization rate is what you're trying to determine with FT/E2 observations and symptom relief. Taking into consideration that only FT is aromatized, FT/E2 ratio is significantly lower than TT/E2 ratios, which points to a HIGHER amount of free test than total test aromatized. Which explains (partially if you disregard SHBG increasing when E2 increases)why FT increases when E2 decreases as less is "used", plus COULD partially explain the clinical impact of E2 level changes.</p><p></p><p>What kind of info have you discovered from FT/E2 patterns?</p><p></p><p>Yes, I agree, this is incredibly complicated, it's like playing whack a mole but with hormones.</p></blockquote><p></p>
[QUOTE="johndoesmith, post: 53461, member: 13404"] Ha, thank you. I enjoy researching this topic, most of my questions are lost as thoughts or questions come to me when I'm driving and I ALWAYS tell myself "I'll remember that for later!" and it never happens. I do recall discussing with you the possibility of Test bound to SHBG unbinding, therefore could aromatize. I imagine that is probably something no one honestly knows at this point in time. I digress, I have noticed a bit of a pattern myself with my free test and E2 readings, E2 is always about 2-3pg/ml higher than my free test. They follow very closely. I imagine that individual aromatization rate is what you're trying to determine with FT/E2 observations and symptom relief. Taking into consideration that only FT is aromatized, FT/E2 ratio is significantly lower than TT/E2 ratios, which points to a HIGHER amount of free test than total test aromatized. Which explains (partially if you disregard SHBG increasing when E2 increases)why FT increases when E2 decreases as less is "used", plus COULD partially explain the clinical impact of E2 level changes. What kind of info have you discovered from FT/E2 patterns? Yes, I agree, this is incredibly complicated, it's like playing whack a mole but with hormones. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
How much testosterone is converted to estradiol?
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