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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
How much testosterone is converted to estradiol?
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<blockquote data-quote="johndoesmith" data-source="post: 53404" data-attributes="member: 13404"><p>32 pg/ml = 3.2 ng/dl. 2.7% of 1183 ng/dl testosterone = 32 ng/dl of E2 which is 320 pg/ml. </p><p></p><p>So it can't be a whole percent, pure math alone shows it's not the case. This also assumes that excretion and metabolism of test and E2 is the same, if E2 is excreted or metabolized faster or slower than test, total levels of both is impossible to use to measure production rate. It could be that estradiol bioaccumulates in the body, thus less testosterone is broken down in order to maintain serum levels of E2. </p><p></p><p>It also assumes that the molecular mass of E2 and test are the same I think. Basically I think it implies that 1 testosterone -> 1 estradiol. That is not the case, testosterone has a higher molar mass than E2 does, so it's more like 2 testosterone -> 1 estradiol. Keep in mind, this is not the correct ratio based on molar mass, and is based on my limited understanding of chemistry. </p><p></p><p>The reason I am asking this is because I want to know how much testosterone is consumed to make estradiol, as in THEORETICALLY how much would an amount of AI enough to prevent ANY testosterone from being converted to E2 increase testosterone levels?</p></blockquote><p></p>
[QUOTE="johndoesmith, post: 53404, member: 13404"] 32 pg/ml = 3.2 ng/dl. 2.7% of 1183 ng/dl testosterone = 32 ng/dl of E2 which is 320 pg/ml. So it can't be a whole percent, pure math alone shows it's not the case. This also assumes that excretion and metabolism of test and E2 is the same, if E2 is excreted or metabolized faster or slower than test, total levels of both is impossible to use to measure production rate. It could be that estradiol bioaccumulates in the body, thus less testosterone is broken down in order to maintain serum levels of E2. It also assumes that the molecular mass of E2 and test are the same I think. Basically I think it implies that 1 testosterone -> 1 estradiol. That is not the case, testosterone has a higher molar mass than E2 does, so it's more like 2 testosterone -> 1 estradiol. Keep in mind, this is not the correct ratio based on molar mass, and is based on my limited understanding of chemistry. The reason I am asking this is because I want to know how much testosterone is consumed to make estradiol, as in THEORETICALLY how much would an amount of AI enough to prevent ANY testosterone from being converted to E2 increase testosterone levels? [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
How much testosterone is converted to estradiol?
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