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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
How long after the T injection are T levels the highest?
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<blockquote data-quote="Cataceous" data-source="post: 152706" data-attributes="member: 38109"><p>This is a common explanation, but it doesn't quite work with respect to TRT. Suppose you have a guy with high SHBG on TRT with constant testosterone levels from frequent injections. What happens if you suddenly make his SHBG low and change nothing else? I think the surprising answer is that, after a stabilization period, total testosterone drops so that free testosterone matches what it was with high SHBG. The reason why is that the rate of testosterone entering the system from injected depots doesn't change. At steady state the rate that testosterone leaves the system must match what's coming in. I explain the argument with an analogy to two tubs of water <a href="https://www.excelmale.com/forum/threads/trt-with-or-without-hcg-and-ai.19002/post-151781" target="_blank">in this thread</a>.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 152706, member: 38109"] This is a common explanation, but it doesn't quite work with respect to TRT. Suppose you have a guy with high SHBG on TRT with constant testosterone levels from frequent injections. What happens if you suddenly make his SHBG low and change nothing else? I think the surprising answer is that, after a stabilization period, total testosterone drops so that free testosterone matches what it was with high SHBG. The reason why is that the rate of testosterone entering the system from injected depots doesn't change. At steady state the rate that testosterone leaves the system must match what's coming in. I explain the argument with an analogy to two tubs of water [URL='https://www.excelmale.com/forum/threads/trt-with-or-without-hcg-and-ai.19002/post-151781']in this thread[/URL]. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
How long after the T injection are T levels the highest?
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