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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
How does high estrogen cause poor erections and low libido?
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<blockquote data-quote="YBWV" data-source="post: 133350" data-attributes="member: 32335"><p>It's not the T to E2 that is the issue in this context it is the DHT:E2.</p><p></p><p>In the case of your example of a guy with TT of 720 and E2 at 23 he could be doing ok, from a hormonal perspective, if he had DHT in the 60's which would seem around average for 5-ar conversion.</p><p></p><p>Problem is that, as with most things, the conversion rate isn't linear so with treatments that raise the total levels of the sex hormones the balance can get thrown off.</p><p></p><p>If the same guy had E2 of 40 (unlikely with TT of 720 but common at higher levels) then he would need DHT of around 120 to 160 which is 50 or 100% over the top of range and would scare many doctors.</p><p></p><p>It's worth remembering that with DHT circulating Serum levels are not an accurate reflection of action at receptors or in target tissue. So, more than ever, subjective improvements in symptoms is what counts rather than levels and ranges.</p><p></p><p>DHT gets ridiculously demonised because it can exacerbate and accelerate the balding process in susceptible individuals.</p><p></p><p>Yet the fact remains that guys need adequate DHT in their Brain and in their Balls for good sexual function.</p></blockquote><p></p>
[QUOTE="YBWV, post: 133350, member: 32335"] It's not the T to E2 that is the issue in this context it is the DHT:E2. In the case of your example of a guy with TT of 720 and E2 at 23 he could be doing ok, from a hormonal perspective, if he had DHT in the 60's which would seem around average for 5-ar conversion. Problem is that, as with most things, the conversion rate isn't linear so with treatments that raise the total levels of the sex hormones the balance can get thrown off. If the same guy had E2 of 40 (unlikely with TT of 720 but common at higher levels) then he would need DHT of around 120 to 160 which is 50 or 100% over the top of range and would scare many doctors. It's worth remembering that with DHT circulating Serum levels are not an accurate reflection of action at receptors or in target tissue. So, more than ever, subjective improvements in symptoms is what counts rather than levels and ranges. DHT gets ridiculously demonised because it can exacerbate and accelerate the balding process in susceptible individuals. Yet the fact remains that guys need adequate DHT in their Brain and in their Balls for good sexual function. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
How does high estrogen cause poor erections and low libido?
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