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[URL unfurl="true"]https://forums.t-nation.com/t/24-hour-tt-profiles-in-young-healthy-functional-men-1970s-1980s/277585/29[/URL]

Related discussion:

Thank you for taking the time to discuss. It is difficult in this medium on something as tedious as this.

Regarding how you restated the claim. I am not claiming they are taking too much testosterone. What I am claiming is this:

In fact, I’ll go a step further and state that

Also the individual reference range that maximizes QOL/longevity appears to be a function of age based on what we know at the moment. 1000 ng/dl may be appropriate for 25 year old version of you, maybe not for the 55 YO version of you. These are subtle points that one should consider so you don’t wreck yourself in the process of trying to optimize.

Graph below shows TT level for symptom resolution may be individual on the lower end of range and the patient needs to understand the unknowns potentially lurking near the high end of the range (300-1200 ng/dl).

Of course everyone is free to seek the treatment they want and I support them. Thanks for taking the time to work through this with me.

<blockquote data-quote="tareload" data-source="post: 223260">[URL unfurl=&quot;true&quot;]https://forums.t-nation.com/t/24-hour-tt-profiles-in-young-healthy-functional-men-1970s-1980s/277585/29[/URL]Related discussion:Thank you for taking the time to discuss.&nbsp; It is difficult in this medium on something as tedious as this.Regarding how you restated the claim.&nbsp; I am not claiming they are taking too much testosterone.&nbsp; What I am claiming is this:In fact, I’ll go a step further and state thatAlso the individual reference range that maximizes QOL/longevity appears to be a function of age based on what we know at the moment.&nbsp;&nbsp; 1000 ng/dl may be appropriate for 25 year old version of you, maybe not for the 55 YO version of you.&nbsp; These are subtle points that one should consider so you don’t wreck yourself in the process of trying to optimize.Graph below shows TT level for symptom resolution may be individual on the lower end of range and the patient needs to understand the unknowns potentially lurking near the high end of the range (300-1200 ng/dl).<img src="https://aws1.discourse-cdn.com/tnation/uploads/default/optimized/4X/9/e/b/9eb4a06615bed84acaa3fc92e578d19df6976dea_2_690x388.jpeg" alt="" class="fr-fic fr-dii fr-draggable " data-size="" style="" />Of course everyone is free to seek the treatment they want and I support them.&nbsp; Thanks for taking the time to work through this with me.</blockquote>

[QUOTE="tareload, post: 223260"] [URL unfurl="true"]https://forums.t-nation.com/t/24-hour-tt-profiles-in-young-healthy-functional-men-1970s-1980s/277585/29[/URL] Related discussion: Thank you for taking the time to discuss. It is difficult in this medium on something as tedious as this. Regarding how you restated the claim. I am not claiming they are taking too much testosterone. What I am claiming is this: In fact, I’ll go a step further and state that Also the individual reference range that maximizes QOL/longevity appears to be a function of age based on what we know at the moment. 1000 ng/dl may be appropriate for 25 year old version of you, maybe not for the 55 YO version of you. These are subtle points that one should consider so you don’t wreck yourself in the process of trying to optimize. Graph below shows TT level for symptom resolution may be individual on the lower end of range and the patient needs to understand the unknowns potentially lurking near the high end of the range (300-1200 ng/dl). [IMG]https://aws1.discourse-cdn.com/tnation/uploads/default/optimized/4X/9/e/b/9eb4a06615bed84acaa3fc92e578d19df6976dea_2_690x388.jpeg[/IMG] Of course everyone is free to seek the treatment they want and I support them. Thanks for taking the time to work through this with me. [/QUOTE]

Verification

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038