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Table 2. Random Forest Importance: Percent Increase in Mean Square Error (Scaled)
[ATTACH=full]19686[/ATTACH]
Table 2 Legend. The importance from random forest prediction of change from baseline to 12 months in hemoglobin, HDL cholesterol, vBMD, sexual desire, and prostate-specific antigen (PSA) using average change in estradiol, DHT, and total testosterone. Larger values indicate a greater predictive value of the indicated hormone in the change in the marker from baseline. Importance is determined by calculating the percent increase in the prediction error (mean square error) when values of the indicated hormone are randomly permuted among participants. Models also include baseline hormones and marker values

[QUOTE="madman, post: 217294, member: 13851"] [B]Table 2. [U]Random Forest Importance[/U]: Percent Increase in Mean Square Error (Scaled) [ATTACH type="full"]19686[/ATTACH] Table 2 Legend. The importance from random forest prediction of change from baseline to 12 months in hemoglobin, HDL cholesterol, vBMD, sexual desire, and prostate-specific antigen (PSA) using average change in estradiol, DHT, and total testosterone. Larger values indicate a greater predictive value of the indicated hormone in the change in the marker from baseline. Importance is determined by calculating the percent increase in the prediction error (mean square error) when values of the indicated hormone are randomly permuted among participants. Models also include baseline hormones and marker values[/B] [/QUOTE]

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TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038