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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
High Testosterone and anxiety
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<blockquote data-quote="madman" data-source="post: 193227" data-attributes="member: 13851"><p>Where your FT ends up comes down to your SHBG and protocol (dose T/injection frequency).</p><p></p><p>The only way to know where it truly sits on such protocol is to have it tested using an accurate assay (Equilibrium Dialysis or Ultrafiltration).</p><p></p><p>Unfortunately using inaccurate assays such as the direct immunoassay or calculated linear law-of-mass action can underestimate/overestimate especially in cases of altered SHBG.</p><p></p><p>Even when using the calculated methods the accuracy of the assays used for TT and SHBG are critical.</p><p></p><p>Driving up TT will increase FT/e2.</p><p></p><p>In your case best you can do is work with what you have available (lab assays) and hitting a higher-end TT will most likely have your FT in a healthy range although it may very well be higher or lower than you think when relying on inaccurate testing methods.</p><p></p><p>If you are hitting a higher-end TT and feeling well overall with no side effects then chances are your FT level is fine where it sits.</p><p></p><p>Keep in mind peak/trough and where your true trough TT/FT/e2 sits on such protocol as this is what you should be paying attention to.</p></blockquote><p></p>
[QUOTE="madman, post: 193227, member: 13851"] Where your FT ends up comes down to your SHBG and protocol (dose T/injection frequency). The only way to know where it truly sits on such protocol is to have it tested using an accurate assay (Equilibrium Dialysis or Ultrafiltration). Unfortunately using inaccurate assays such as the direct immunoassay or calculated linear law-of-mass action can underestimate/overestimate especially in cases of altered SHBG. Even when using the calculated methods the accuracy of the assays used for TT and SHBG are critical. Driving up TT will increase FT/e2. In your case best you can do is work with what you have available (lab assays) and hitting a higher-end TT will most likely have your FT in a healthy range although it may very well be higher or lower than you think when relying on inaccurate testing methods. If you are hitting a higher-end TT and feeling well overall with no side effects then chances are your FT level is fine where it sits. Keep in mind peak/trough and where your true trough TT/FT/e2 sits on such protocol as this is what you should be paying attention to. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
High Testosterone and anxiety
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