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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
High SHBG
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<blockquote data-quote="madman" data-source="post: 130875" data-attributes="member: 13851"><p>Again both methods have their flaws regarding measurement of Free Testosterone:</p><p></p><p>Calculated Free Testosterone (Vermuelen) method tends to <strong><span style="color: rgb(184, 49, 47)">overestimate</span></strong> and the direct analog immunoassay RIA (radio immunoassay) or EIA (enzyme immunoassay) tends to <span style="color: rgb(184, 49, 47)"><strong>underestimate</strong> </span>when compared against the gold standard <span style="color: rgb(250, 197, 28)">EQUILIBRIUM DIALYSIS.</span></p><p></p><p>To obtain the most accurate value of ones Free Testosterone levels you would need to get the equilibrium dialysis:</p><p></p><p><a href="https://www.labcorp.com/test-menu/35521/testosterone-free-mass-spectrometry-equilibrium-dialysis-endocrine-sciences" target="_blank">500726: Testosterone, Free, Mass Spectrometry... | LabCorp</a></p><p></p><p></p><p>Or the equilibrium ultrafiltration:</p><p></p><p><a href="https://www.labcorp.com/test-menu/35516/testosterone-free-equilibrium-ultrafiltration-with-total-testosterone-lc-ms-ms" target="_blank">070038: Testosterone, Free, Equilibrium Ultrafiltration... | LabCorp</a></p><p></p><p></p><p>Most importantly if you are always basing how you feel compared to lab work when looking at your free testosterone levels than in cases of men with low or high SHBG I would definitely be using equilibrium dialysis if you want to truly gauge how your FT levels are affected when adjusting trt protocol whether increasing/decreasing testosterone dose.</p></blockquote><p></p>
[QUOTE="madman, post: 130875, member: 13851"] Again both methods have their flaws regarding measurement of Free Testosterone: Calculated Free Testosterone (Vermuelen) method tends to [B][COLOR=rgb(184, 49, 47)]overestimate[/COLOR][/B] and the direct analog immunoassay RIA (radio immunoassay) or EIA (enzyme immunoassay) tends to [COLOR=rgb(184, 49, 47)][B]underestimate[/B] [/COLOR]when compared against the gold standard [COLOR=rgb(250, 197, 28)]EQUILIBRIUM DIALYSIS.[/COLOR] To obtain the most accurate value of ones Free Testosterone levels you would need to get the equilibrium dialysis: [URL='https://www.labcorp.com/test-menu/35521/testosterone-free-mass-spectrometry-equilibrium-dialysis-endocrine-sciences']500726: Testosterone, Free, Mass Spectrometry... | LabCorp[/URL] Or the equilibrium ultrafiltration: [URL='https://www.labcorp.com/test-menu/35516/testosterone-free-equilibrium-ultrafiltration-with-total-testosterone-lc-ms-ms']070038: Testosterone, Free, Equilibrium Ultrafiltration... | LabCorp[/URL] Most importantly if you are always basing how you feel compared to lab work when looking at your free testosterone levels than in cases of men with low or high SHBG I would definitely be using equilibrium dialysis if you want to truly gauge how your FT levels are affected when adjusting trt protocol whether increasing/decreasing testosterone dose. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
High SHBG
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