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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
High SHBG
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<blockquote data-quote="madman" data-source="post: 129909" data-attributes="member: 13851"><p>If anything get retested using a more accurate assay as the one you had done for Free Testosterone -<strong><span style="color: rgb(184, 49, 47)">Direct analog enzyme immunoassay (EIA)</span></strong> is inaccurate and tends to underestimate.</p><p></p><p>In your situation with such a high SHBG get the- <strong><span style="color: rgb(184, 49, 47)">Free: equilibrium ultrafiltration; total: liquid chromatography/tandem mass spectrometry (LC/MS-MS)</span></strong></p><p></p><p><span style="color: rgb(0, 0, 0)">I would rather use the calculated (Vermulen) method for Free & Bioavailable Testosterone than pay for the <strong><span style="color: rgb(184, 49, 47)">Direct analog enzyme immunoassay (EIA) </span></strong></span></p><p></p><p>It can be accessed online for free <a href="http://www.issam.ch/freetesto.htm" target="_blank">Free & Bioavailable Testosterone calculator</a></p><p></p><p>Even though your TT 951 ng/dL and your SHBG 73.8 nmol/L if we use the calculated method above.....your FT is only <strong><span style="color: rgb(184, 49, 47)">12.8 ng/dL= 1.35% </span></strong>and your BT is only 31.7%</p><p></p><p>Although your TT 951 ng/dL may seem robust your FT is on the lower end due to your very high SHBG.</p><p></p><p>TT is good to know but FT is what truly matters as it is the unbound active fraction of testosterone and FT is 2-3% of TT.....most men do well having FT in the 2-3% range.</p></blockquote><p></p>
[QUOTE="madman, post: 129909, member: 13851"] If anything get retested using a more accurate assay as the one you had done for Free Testosterone -[B][COLOR=rgb(184, 49, 47)]Direct analog enzyme immunoassay (EIA)[/COLOR][/B] is inaccurate and tends to underestimate. In your situation with such a high SHBG get the- [B][COLOR=rgb(184, 49, 47)]Free: equilibrium ultrafiltration; total: liquid chromatography/tandem mass spectrometry (LC/MS-MS)[/COLOR][/B] [COLOR=rgb(0, 0, 0)]I would rather use the calculated (Vermulen) method for Free & Bioavailable Testosterone than pay for the [B][COLOR=rgb(184, 49, 47)]Direct analog enzyme immunoassay (EIA) [/COLOR][/B][/COLOR] It can be accessed online for free [URL='http://www.issam.ch/freetesto.htm']Free & Bioavailable Testosterone calculator[/URL] Even though your TT 951 ng/dL and your SHBG 73.8 nmol/L if we use the calculated method above.....your FT is only [B][COLOR=rgb(184, 49, 47)]12.8 ng/dL= 1.35% [/COLOR][/B]and your BT is only 31.7% Although your TT 951 ng/dL may seem robust your FT is on the lower end due to your very high SHBG. TT is good to know but FT is what truly matters as it is the unbound active fraction of testosterone and FT is 2-3% of TT.....most men do well having FT in the 2-3% range. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
High SHBG
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