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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
High SHBG concerns and Ignorant doctors
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<blockquote data-quote="madman" data-source="post: 116115" data-attributes="member: 13851"><p>You state you found out on 5/15/2018 through blood work that you have very low TT/FT (although you did not provide ranges) and your e2 was tested but using the wrong testing method as it need to be the estradiol sensitive assay -LC/MS-MS and you did not have your SHBG tested until next set of labs.</p><p></p><p>You than state that the clinic started you on trt (210mg once weekly) along with 1000 IU HCG (split twice weekly).....so to me at first is seems like a standard t-mill protocol regarding starting a patient 0n 200+mg testosterone once weekly as you did not have SHBG tested on your first set of labs so how would the clinic have known you had high SHBG pre-trt as SHBG was not done until following blood work through your primary doctor after you started protocol from the clinic.</p><p></p><p>I am going to say that from the way your post is written that you started your trt protocol right around the time you found out you had low t from pre-trt blood work on 5/15/2018.....you than went for follow up blood work through your primary doctor so I would think you have already been on trt for 6-8 weeks as it is now 7/23/2018 and on your most recent blood work your TT is 1180 ng/dl and your SHBG is absurdly high at 76.6 nmol/L which basically has either not budged since starting your protocol or your pre-trt SHBG was actually higher than 76.6 nmol/L and it has dropped some.</p><p></p><p>Either way even though you did not have your FT tested which is critical to know as it is the unbound active fraction of testosterone even though your TT of 1180 ng/dL may seem really high for a trough reading because your SHBG is still absurdly high your FT will still be low even at that TT level and as VC stated higher doses of testosterone injected once weekly are usually effective to help lower high SHBG .....BUT yours has not budged unless it was higher than 76.6 nmol/L pre-trt.....if I am correct that you have already been on this protocol for 6-8 weeks.</p><p></p><p>You need to have your FT tested to see where your levels sit which I would say are still low due to your absurdly high SHBG.</p><p></p><p>Even than one can use the Free % Bioavailable Testosterone calculator (calculated method for free testosterone) and if you take your TT of 1180 ng/dL and your SHBG of 76.6 nmol/L along with albumin which is set as 4.3 g/dl (as the mean in most men) than your FREE T is still very low at 1.39% and your BIOAVAILABLE T would be 32.7%.</p><p></p><p><a href="http://www.issam.ch/freetesto.htm" target="_blank">http://www.issam.ch/freetesto.htm</a></p><p>.................................................</p><p></p><p>Ideally most men need their FT to be 2-3% of TT to experience the beneficial effects of testosterone.</p></blockquote><p></p>
[QUOTE="madman, post: 116115, member: 13851"] You state you found out on 5/15/2018 through blood work that you have very low TT/FT (although you did not provide ranges) and your e2 was tested but using the wrong testing method as it need to be the estradiol sensitive assay -LC/MS-MS and you did not have your SHBG tested until next set of labs. You than state that the clinic started you on trt (210mg once weekly) along with 1000 IU HCG (split twice weekly).....so to me at first is seems like a standard t-mill protocol regarding starting a patient 0n 200+mg testosterone once weekly as you did not have SHBG tested on your first set of labs so how would the clinic have known you had high SHBG pre-trt as SHBG was not done until following blood work through your primary doctor after you started protocol from the clinic. I am going to say that from the way your post is written that you started your trt protocol right around the time you found out you had low t from pre-trt blood work on 5/15/2018.....you than went for follow up blood work through your primary doctor so I would think you have already been on trt for 6-8 weeks as it is now 7/23/2018 and on your most recent blood work your TT is 1180 ng/dl and your SHBG is absurdly high at 76.6 nmol/L which basically has either not budged since starting your protocol or your pre-trt SHBG was actually higher than 76.6 nmol/L and it has dropped some. Either way even though you did not have your FT tested which is critical to know as it is the unbound active fraction of testosterone even though your TT of 1180 ng/dL may seem really high for a trough reading because your SHBG is still absurdly high your FT will still be low even at that TT level and as VC stated higher doses of testosterone injected once weekly are usually effective to help lower high SHBG .....BUT yours has not budged unless it was higher than 76.6 nmol/L pre-trt.....if I am correct that you have already been on this protocol for 6-8 weeks. You need to have your FT tested to see where your levels sit which I would say are still low due to your absurdly high SHBG. Even than one can use the Free % Bioavailable Testosterone calculator (calculated method for free testosterone) and if you take your TT of 1180 ng/dL and your SHBG of 76.6 nmol/L along with albumin which is set as 4.3 g/dl (as the mean in most men) than your FREE T is still very low at 1.39% and your BIOAVAILABLE T would be 32.7%. [URL]http://www.issam.ch/freetesto.htm[/URL] ................................................. Ideally most men need their FT to be 2-3% of TT to experience the beneficial effects of testosterone. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
High SHBG concerns and Ignorant doctors
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