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I try to keep my HCT below 52%, usually between 49 - 52%, my urologist is good up to 55%, he has not seen issues with higher HCT from HRT. My BP is 120's/70's, use a BB for essential tremor and 1 mg of lisinopril to reduce ANG II. I can't tell if my HCT is 49 or 55%. No difference in anything perceived or measured. Best approach is to figure out how often you need to donate to keep HCT in your comfort zone, if your T dosing is consistent, then it will generally be every X weeks. I use propranolol 30 mg before bed and 20 mg upon waking. Nothing during the day so it doesn't impair functional capacity. Best approach to BP control is an ARB or ACEi, as long as you're not at risk for AE. ANG II is what drives adverse cardiac remodeling. This is particularly important if ND is part of your HRT.