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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
high hematocrit/hemoglobin - what to do
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<blockquote data-quote="tareload" data-source="post: 216250"><p>===</p><p>EDIT:</p><p>[USER=3]@Nelson Vergel[/USER]</p><p></p><p>i really enjoyed how they treated the concept of optimal Hct at rest vs under constraint of constant cardiac power. Perhaps something to weave into your articles emphasizing the ramifications for TRT patients in different demographic and age groups.</p><p></p><p>===</p><p></p><p>My 2 cents...</p><p>An excellent recent article that examines the tradeoffs associated with longevity vs performance. Hedge accordingly based on your specific circumstances.</p><p></p><p>[URL unfurl="true"]https://www.nature.com/articles/s41598-021-83427-2[/URL]</p><p>[URL unfurl="true"]https://www.nature.com/articles/s41598-021-83427-2.pdf[/URL]</p><p></p><p></p><h2>Abstract</h2><p><em>In humans and higher animals, a trade-off between sufficiently high erythrocyte concentrations to bind oxygen and sufficiently low blood viscosity to allow rapid blood flow has been achieved during evolution. Optimal hematocrit theory has been successful in predicting hematocrit (HCT) values of about 0.3–0.5, in very good agreement with the normal values observed for humans and many animal species. </em><u><span style="font-size: 18px"><em><span style="font-family: 'Book Antiqua'"><u>However, according to those calculations, the optimal value should be independent of the mechanical load of the body. This is in contradiction to the exertional increase in HCT observed in some animals called natural blood dopers and to the illegal practice of blood boosting in high-performance sports. Here, we present a novel calculation to predict the optimal HCT value under the constraint of constant cardiac power and compare it to the optimal value obtained for constant driving pressure. </u></span></em></span></u><em>We show that the optimal HCT under constant power ranges from 0.5 to 0.7, in agreement with observed values in natural blood dopers at exertion. We use this result to explain the tendency to better exertional performance at an increased HCT.</em></p><p></p><p></p><p></p><p>[ATTACH=full]19298[/ATTACH]</p><p></p><p>[ATTACH=full]19297[/ATTACH]</p></blockquote><p></p>
[QUOTE="tareload, post: 216250"] === EDIT: [USER=3]@Nelson Vergel[/USER] i really enjoyed how they treated the concept of optimal Hct at rest vs under constraint of constant cardiac power. Perhaps something to weave into your articles emphasizing the ramifications for TRT patients in different demographic and age groups. === My 2 cents... An excellent recent article that examines the tradeoffs associated with longevity vs performance. Hedge accordingly based on your specific circumstances. [URL unfurl="true"]https://www.nature.com/articles/s41598-021-83427-2[/URL] [URL unfurl="true"]https://www.nature.com/articles/s41598-021-83427-2.pdf[/URL] [HEADING=1]Abstract[/HEADING] [I]In humans and higher animals, a trade-off between sufficiently high erythrocyte concentrations to bind oxygen and sufficiently low blood viscosity to allow rapid blood flow has been achieved during evolution. Optimal hematocrit theory has been successful in predicting hematocrit (HCT) values of about 0.3–0.5, in very good agreement with the normal values observed for humans and many animal species. [/I][U][SIZE=18px][I][FONT=Book Antiqua][U]However, according to those calculations, the optimal value should be independent of the mechanical load of the body. This is in contradiction to the exertional increase in HCT observed in some animals called natural blood dopers and to the illegal practice of blood boosting in high-performance sports. Here, we present a novel calculation to predict the optimal HCT value under the constraint of constant cardiac power and compare it to the optimal value obtained for constant driving pressure. [/U][/FONT][/I][/SIZE][/U][I]We show that the optimal HCT under constant power ranges from 0.5 to 0.7, in agreement with observed values in natural blood dopers at exertion. We use this result to explain the tendency to better exertional performance at an increased HCT.[/I] [ATTACH type="full" alt="1643391263133.png"]19298[/ATTACH] [ATTACH type="full" alt="1643391141980.png"]19297[/ATTACH] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
high hematocrit/hemoglobin - what to do
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