You did not. The studies you posted were not about people on TRT, so why was their HCT elevated in the first place? It matters.
You are focussing on a symptom, ignoring it’s specific medical context, to draw a conclusion for a fundamentally different medical context. Ironically, the only fact to conclude is that the symptom presented itself outside of the context of TRT.
Doing so, you are actually applying a research model of the human body with fixed variables because it is easier to understand and it makes it possible to draw conclusions from the data that is already there (elevated HCT equals higher blood viscosity equals cvd).
To me it is a mistake often made in medical research and it sets us back by creating false dogma’s that hurt patients while trying to help them.
In my opinion, the only conclusion to draw from this is that we need specific research to create guidelines that aren’t arbitrary and to not be dogmatic about doing so. Until then it is risk to calculate depending on the medical context of the patient.
You make these calculations based on the assumption that high HCT is the culprit, I make them based on other known culprits such as hypertension, crp-levels, insuline resistance, etc.
I will leave it at that because I feel we are going in circles. I appreciate our discussion about this. Best wishes to you as well!
