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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
high hematocrit/hemoglobin - what to do
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<blockquote data-quote="tareload" data-source="post: 216180"><p>And I'm sure you are well aware of this article and many others like it:</p><p>[URL unfurl="true"]https://www.bmj.com/content/311/7003/485[/URL]</p><p></p><p><em>When we are told that “there is no evidence that A causes B” we should first ask whether absence of evidence means simply that there is no information at all. If there are data we should look for quantification of the association rather than just a P value. Where risks are small P values may well mislead: confidence intervals are likely to be wide, indicating considerable uncertainty. While we can never prove the absence of a relation, when necessary we should seek evidence against the link between A and B—for example, from case-control studies. The importance of carrying out such studies will relate to the seriousness of the postulated effect and how widespread is the exposure in the population.</em></p><p></p><p></p><p>TRT/TOT/blah blah blah is a large uncontrolled experiment. Caution is in order when the probability is high that you'll learn your individual response before you get RCT evidence to point at.</p><p></p><p>Thanks for your thoughts.</p><p></p><p>EDIT: By the way this guy with the comment on the article at the bottom is an absolute stud.</p><p></p><p>[ATTACH=full]19284[/ATTACH]</p></blockquote><p></p>
[QUOTE="tareload, post: 216180"] And I'm sure you are well aware of this article and many others like it: [URL unfurl="true"]https://www.bmj.com/content/311/7003/485[/URL] [I]When we are told that “there is no evidence that A causes B” we should first ask whether absence of evidence means simply that there is no information at all. If there are data we should look for quantification of the association rather than just a P value. Where risks are small P values may well mislead: confidence intervals are likely to be wide, indicating considerable uncertainty. While we can never prove the absence of a relation, when necessary we should seek evidence against the link between A and B—for example, from case-control studies. The importance of carrying out such studies will relate to the seriousness of the postulated effect and how widespread is the exposure in the population.[/I] TRT/TOT/blah blah blah is a large uncontrolled experiment. Caution is in order when the probability is high that you'll learn your individual response before you get RCT evidence to point at. Thanks for your thoughts. EDIT: By the way this guy with the comment on the article at the bottom is an absolute stud. [ATTACH type="full"]19284[/ATTACH] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
high hematocrit/hemoglobin - what to do
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