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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
High Hematocrit and sexual function
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<blockquote data-quote="Blackhawk" data-source="post: 172400" data-attributes="member: 16042"><p>[USER=38334]@SkyWarn[/USER]</p><p></p><p><a href="https://en.wikipedia.org/wiki/Grapefruit%E2%80%93drug_interactions" target="_blank">Grapefruit–drug interactions - Wikipedia</a></p><p></p><p>Grapefuit juice is a CYP3A inhibitor which affects the clearance of many more drugs than just statins, This can be a very serious effect. In the case of some statins it can effectively increase the dosage by a factor of 40. This results in a toxic level built up, unable to clear from the body. This video has this 40 fold reference: <a href="https://www.mskcc.org/cancer-care/diagnosis-treatment/symptom-management/integrative-medicine/herbs" target="_blank">About Herbs, Botanicals & Other Products MSK cancer research</a></p><p></p><p>CYP3 enhances the clearance of drugs and toxins from the body. If you inhibit its effect, less is cleared, more stays in the body. There are also CYP3A inducers which induce a higher rate of clearance.</p><p></p><p>It will indeed screw up your dosage of statin and is contraindicated.</p><p></p><p></p><p></p><p>One chart (there are many): <a href="https://www.mayocliniclabs.com/it-mmfiles/Cytochrome_P450_3A4_and_3A5_Known_Drug_Interaction_Chart.pdf" target="_blank">https://www.mayocliniclabs.com/it-mmfiles/Cytochrome_P450_3A4_and_3A5_Known_Drug_Interaction_Chart.pdf</a></p><p></p><p>There are other CYP substrates, inhibitors and reducers than can be pertineient in drug, supplement and food interactions: <a href="https://www.fda.gov/drugs/drug-interactions-labeling/drug-development-and-drug-interactions-table-substrates-inhibitors-and-inducers" target="_blank">Table of Substrates, Inhibitors and Inducers</a></p></blockquote><p></p>
[QUOTE="Blackhawk, post: 172400, member: 16042"] [USER=38334]@SkyWarn[/USER] [URL="https://en.wikipedia.org/wiki/Grapefruit%E2%80%93drug_interactions"]Grapefruit–drug interactions - Wikipedia[/URL] Grapefuit juice is a CYP3A inhibitor which affects the clearance of many more drugs than just statins, This can be a very serious effect. In the case of some statins it can effectively increase the dosage by a factor of 40. This results in a toxic level built up, unable to clear from the body. This video has this 40 fold reference: [URL='https://www.mskcc.org/cancer-care/diagnosis-treatment/symptom-management/integrative-medicine/herbs']About Herbs, Botanicals & Other Products MSK cancer research[/URL] CYP3 enhances the clearance of drugs and toxins from the body. If you inhibit its effect, less is cleared, more stays in the body. There are also CYP3A inducers which induce a higher rate of clearance. It will indeed screw up your dosage of statin and is contraindicated. One chart (there are many): [URL]https://www.mayocliniclabs.com/it-mmfiles/Cytochrome_P450_3A4_and_3A5_Known_Drug_Interaction_Chart.pdf[/URL] There are other CYP substrates, inhibitors and reducers than can be pertineient in drug, supplement and food interactions: [URL='https://www.fda.gov/drugs/drug-interactions-labeling/drug-development-and-drug-interactions-table-substrates-inhibitors-and-inducers']Table of Substrates, Inhibitors and Inducers[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
High Hematocrit and sexual function
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