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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
High HCT - trying to decide whether to get phlebotomy
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<blockquote data-quote="Biggee" data-source="post: 165283" data-attributes="member: 39342"><p>I have been on TRT for over ten years and my lab values always hover around 56 Hct and 19 Hgb. I never paid much attention to it but now that I am mid 40s I am starting to worry more about those things. As far as I can tell, I have never had any ill effects from those levels. There seems to be a broad consensus to stay closer to the normal range but when I looked at a study of people living at high altitude, their normal range was 45 to 61%. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=11682015" target="_blank">Normal hematological values for healthy persons living at 4000 meters in Bolivia. - PubMed - NCBI</a>) I also heard that for people living at higher altitude in the US, some doctors consider 55% Hct normal, no treatment required.</p><p></p><p>But just because the body is able to adapt, does not mean that it's a good idea. So then I looked whether there are long term negative consequences associated with adaptation to high altitudes but, if anything, the opposite seems to be the case: no negative effects and some protective effects on coronary heart disease and stroke mortality. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/19635973" target="_blank">Lower mortality from coronary heart disease and stroke at higher altitudes in Switzerland. - PubMed - NCBI</a>)</p><p></p><p>I also read that starting around 60% Hct, blood viscosity increases exponentially which interestingly is the same as the upper limit of normal in high altitude adjusted individuals. But what about the 51% - 60% range. It's definitely not "normal" but does it require intervention?</p></blockquote><p></p>
[QUOTE="Biggee, post: 165283, member: 39342"] I have been on TRT for over ten years and my lab values always hover around 56 Hct and 19 Hgb. I never paid much attention to it but now that I am mid 40s I am starting to worry more about those things. As far as I can tell, I have never had any ill effects from those levels. There seems to be a broad consensus to stay closer to the normal range but when I looked at a study of people living at high altitude, their normal range was 45 to 61%. ([URL="https://www.ncbi.nlm.nih.gov/pubmed/?term=11682015"]Normal hematological values for healthy persons living at 4000 meters in Bolivia. - PubMed - NCBI[/URL]) I also heard that for people living at higher altitude in the US, some doctors consider 55% Hct normal, no treatment required. But just because the body is able to adapt, does not mean that it's a good idea. So then I looked whether there are long term negative consequences associated with adaptation to high altitudes but, if anything, the opposite seems to be the case: no negative effects and some protective effects on coronary heart disease and stroke mortality. ([URL="https://www.ncbi.nlm.nih.gov/pubmed/19635973"]Lower mortality from coronary heart disease and stroke at higher altitudes in Switzerland. - PubMed - NCBI[/URL]) I also read that starting around 60% Hct, blood viscosity increases exponentially which interestingly is the same as the upper limit of normal in high altitude adjusted individuals. But what about the 51% - 60% range. It's definitely not "normal" but does it require intervention? [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
High HCT - trying to decide whether to get phlebotomy
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