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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
High Estradiol - Labs - Advice Request
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<blockquote data-quote="madman" data-source="post: 202027" data-attributes="member: 13851"><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/effects-of-dutasteride-on-sex-hormones-and-cerebrospinal-steroids-in-patients-treated-for-bph.23280/#post-199722[/URL]</p><p></p><p><strong><em>*The adverse effects of 5ARI on the sexual sphere are mainly ascribed to their known <u>antiandrogenic properties</u>. However, the possible mechanisms of action by which 5ARI causes adverse effects on sexuality have not still clearly elucidated.</em></strong></p><p><strong><em></em></strong></p><p><strong><em>*<strong><em>Experimental evidence conducted on both animals and humans have also suggested that the onset of adverse sexual effects after treatment with 5ARI may be partly attributable to their central effect and, in particular, to the <u>5ARI ability to inhibit the levels of some CNS neurosteroids probably implicated in the regulation of sexual desire and erection</u></em></strong></em></strong></p><p><strong><em></em></strong></p><p><strong><em>*These neurosteroids, which are produced by both the testis and the CNS, are implicated not only in the <u>regulation of sexual function but also in cognitive, behavioral, and reproductive aspects, and possibly also in neurodegenerative diseases</u></em></strong></p></blockquote><p></p>
[QUOTE="madman, post: 202027, member: 13851"] [URL unfurl="true"]https://www.excelmale.com/forum/threads/effects-of-dutasteride-on-sex-hormones-and-cerebrospinal-steroids-in-patients-treated-for-bph.23280/#post-199722[/URL] [B][I]*The adverse effects of 5ARI on the sexual sphere are mainly ascribed to their known [U]antiandrogenic properties[/U]. However, the possible mechanisms of action by which 5ARI causes adverse effects on sexuality have not still clearly elucidated. *[B][I]Experimental evidence conducted on both animals and humans have also suggested that the onset of adverse sexual effects after treatment with 5ARI may be partly attributable to their central effect and, in particular, to the [U]5ARI ability to inhibit the levels of some CNS neurosteroids probably implicated in the regulation of sexual desire and erection[/U][/I][/B] *These neurosteroids, which are produced by both the testis and the CNS, are implicated not only in the [U]regulation of sexual function but also in cognitive, behavioral, and reproductive aspects, and possibly also in neurodegenerative diseases[/U][/I][/B] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
High Estradiol - Labs - Advice Request
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