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Unfortunately for me my first go around with T caused significant cystic and nodular acne and I was referred to a dermatologist.  I was put on 80 mg of accutane daily for 7 months.  I'm not going to get into it but it was a horrible experience and I would never recommend this course to anyone.

I have since been very regimented with my skin care.  Along with washing with both cetaphil and acne medicated soap 2-4 times a day, I also use a topical medication nightly.  Despite these effort the acne has returned (although not nearly as bad yet) once I started trt.  This is why I'm terrified to increasing my dose.

Although I haven't found a lot of literature on sub q injections, the fact that Dr. Crisler has had success with some of his patients is reason enough to at least try for an extended period of time.  I will be doing my next blood work in about 2 months so I'll see what the numbers say then.  I may try your method Nelson if I find that subq injections don't help with my estrodiol.

While I do expect that my problems with acne will increase with upping the dose is it inevitable that i will also become more muscular?  The close friends I mentioned in the first post are actually women that train at my gym so I doubt that they'd be jealous of my size lol.


TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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