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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Hematocrit drives Blood Viscosity- Does that Matter in Men on TRT? Effect of Altitude?
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<blockquote data-quote="tareload" data-source="post: 143553"><p>Have you measured your hemochromatosis (HH) status? Transferrin saturation? There's a reasonable PCR test to check your HH status: </p><p></p><p><a href="https://www.labcorp.com/test-menu/27711/hereditary-hemochromatosis-dna-analysis" target="_blank">Labcorp HH DNA assay</a></p><p></p><p>You sound frustrated and I am empathetic to you. I hope you get the results you are looking for and I realize it can be a hard journey. I wish you peace and a life free from suffering. </p><p></p><p>I read your Dr. is Dr. Saya and he can discuss with you the many people that have had benefit from dose reduction. I benefited but of course mileage varies. I am on the journey just like you. If your iron regulation/metabolism is dysfunctional (as is the case with HH), your HgB and Hct will be very sensitive to TRT dosage and its effect on hepcidin:</p><p></p><p>Worth a consideration. Happy reading:</p><p><a href="https://www.amjmed.com/article/S0002-9343(16)30320-5/abstract" target="_blank">Hemochromatosis Unveiled by Testosterone Replacement in a Man with Hypogonadism</a></p><p></p><p><a href="https://aasldpubs.onlinelibrary.wiley.com/doi/pdf/10.1002/hep.26648" target="_blank">Testosterone Perturbs Systemic Iron Balance ThroughActivation of Epidermal Growth Factor ReceptorSignaling in the Liver and Repression of Hepcidin</a></p><p></p><p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227985/" target="_blank">Regulation of the Iron Homeostatic Hormone Hepcidin</a></p><p></p><p><a href="https://onlinelibrary.wiley.com/doi/full/10.1111/acel.12052" target="_blank">Testosterone administration inhibits hepcidin transcription and is associated with increased iron incorporation into red blood cells</a></p></blockquote><p></p>
[QUOTE="tareload, post: 143553"] Have you measured your hemochromatosis (HH) status? Transferrin saturation? There's a reasonable PCR test to check your HH status: [URL='https://www.labcorp.com/test-menu/27711/hereditary-hemochromatosis-dna-analysis']Labcorp HH DNA assay[/URL] You sound frustrated and I am empathetic to you. I hope you get the results you are looking for and I realize it can be a hard journey. I wish you peace and a life free from suffering. I read your Dr. is Dr. Saya and he can discuss with you the many people that have had benefit from dose reduction. I benefited but of course mileage varies. I am on the journey just like you. If your iron regulation/metabolism is dysfunctional (as is the case with HH), your HgB and Hct will be very sensitive to TRT dosage and its effect on hepcidin: Worth a consideration. Happy reading: [URL='https://www.amjmed.com/article/S0002-9343(16)30320-5/abstract']Hemochromatosis Unveiled by Testosterone Replacement in a Man with Hypogonadism[/URL] [URL='https://aasldpubs.onlinelibrary.wiley.com/doi/pdf/10.1002/hep.26648']Testosterone Perturbs Systemic Iron Balance ThroughActivation of Epidermal Growth Factor ReceptorSignaling in the Liver and Repression of Hepcidin[/URL] [URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227985/']Regulation of the Iron Homeostatic Hormone Hepcidin[/URL] [URL='https://onlinelibrary.wiley.com/doi/full/10.1111/acel.12052']Testosterone administration inhibits hepcidin transcription and is associated with increased iron incorporation into red blood cells[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Hematocrit drives Blood Viscosity- Does that Matter in Men on TRT? Effect of Altitude?
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