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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Help with urinary issues while on TRT - BPH or 'overactive pelvic floor muscle'
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<blockquote data-quote="madman" data-source="post: 192788" data-attributes="member: 13851"><p>Finally!</p><p></p><p>As you can clearly see not only is your trough TT absurdly high 1362 ng/dL on such a whopping dose of T 200g/week but more importantly, your trough FT is high, and even than I would put money on it that it is higher than you think as unfortunately, you had it tested using the piss poor direct immunoassay.</p><p></p><p>Although TT is important to know FT is what truly matters as it is the active unbound fraction of testosterone responsible for the positive effects.</p><p></p><p>When testing FT it is critical to have it done using the most accurate assays such as the gold standard Equilibrium Dialysis or Ultrafiltration if you want to know where your FT level truly sits on such protocol.</p><p></p><p>You were on a horrible protocol which would be the cookie-cutter Tmill recipe type which is high dosed T injected once weekly with an AI let alone absurd dose thrown in to boot!</p><p></p><p>Sad that these doctors would start someone on such a high dose of T than throw an AI in the mix right off the hop.</p><p></p><p>Seeing as you were hitting such an absurdly high TT trough of almost 1400 ng/dL and high FT your TT/FT peak levels post-injection (8-12 hrs) and during the first few days will be insanely high and drive up estradiol.</p><p></p><p>Hard to give any further advice as we have absolutely no clue where your trough TT/FT/e2 levels sit as of now on your current protocol as you did not post labs?</p><p></p><p>You need to look into possibly tweaking your protocol (dose T/injection frequency) and may very well fair better lowering your overall weekly dose of T and injecting more frequently depending on where your current protocol (160 mg/week T) has your trough TT/FT/e2 levels</p><p></p><p>The downfall of injecting such a large dose of T once weekly is not only will there be a big difference in the peak--->trough as TT/FT levels will be sky-high early in the week only to be followed by much lower levels come weeks end and in your case still too high come weeks end (trough) let alone blood levels will not be as stable throughout the week.</p></blockquote><p></p>
[QUOTE="madman, post: 192788, member: 13851"] Finally! As you can clearly see not only is your trough TT absurdly high 1362 ng/dL on such a whopping dose of T 200g/week but more importantly, your trough FT is high, and even than I would put money on it that it is higher than you think as unfortunately, you had it tested using the piss poor direct immunoassay. Although TT is important to know FT is what truly matters as it is the active unbound fraction of testosterone responsible for the positive effects. When testing FT it is critical to have it done using the most accurate assays such as the gold standard Equilibrium Dialysis or Ultrafiltration if you want to know where your FT level truly sits on such protocol. You were on a horrible protocol which would be the cookie-cutter Tmill recipe type which is high dosed T injected once weekly with an AI let alone absurd dose thrown in to boot! Sad that these doctors would start someone on such a high dose of T than throw an AI in the mix right off the hop. Seeing as you were hitting such an absurdly high TT trough of almost 1400 ng/dL and high FT your TT/FT peak levels post-injection (8-12 hrs) and during the first few days will be insanely high and drive up estradiol. Hard to give any further advice as we have absolutely no clue where your trough TT/FT/e2 levels sit as of now on your current protocol as you did not post labs? You need to look into possibly tweaking your protocol (dose T/injection frequency) and may very well fair better lowering your overall weekly dose of T and injecting more frequently depending on where your current protocol (160 mg/week T) has your trough TT/FT/e2 levels The downfall of injecting such a large dose of T once weekly is not only will there be a big difference in the peak--->trough as TT/FT levels will be sky-high early in the week only to be followed by much lower levels come weeks end and in your case still too high come weeks end (trough) let alone blood levels will not be as stable throughout the week. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Help with urinary issues while on TRT - BPH or 'overactive pelvic floor muscle'
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