I would like to post an update here, as my suspect of being an AI over-responder has been confirmed and maybe this could contribute to the new trend of going completely off any AI, which I don't agree with, despite the fact I've tanked my E2 once.
So I've re-tested after cutting on half the HCG dose and being on 17.5 mg of T enanthate and 50 IU of HCG 3 x week , and these are the results:
Total T = 1386.8 ng/dL (241 – 827 ng/dL)
Free T = 25.2 pg/mL (8.5 - 30.4 pg/mL)
Estradiol = 102.14 pg/mL (10 – 40 pg/mL)
Prolactin = 26.91 ng/mL (2.1 – 17.7 ng/mL)
TSH = 2.075 uUI/mL (0.35 – 5.5 uUI/mL)
Free T3 = 3.1 pg/mL (2.3 – 4.2 pg/mL)
Free T4 = 0.89 ng/dL (0.89 – 1.76 ng/dL)
SHBG = 23 nmol/L (10 – 80 nmol/L)
Cortisol = 16.69 ug/dL (AM: 4.3 - 22.4 ug/dL)
IGF-1 = 136.0 ng/mL (Age 31-35: 88-246 ng/mL)
DHEA-S = 209.3 ug/dL (35 – 550 ug/dL)
Pregnenolone= 211.5 ng/dL (38 – 248 ng/dL)
As you can see, despite the fact of lifting heavy 4 times x week (200 kg 6 reps of squat, 140 kg 6 reps of bench press, 170 kg 6 reps of deadlifts, 75 kg 6 resp of overhead press) and being quite muscular (180 cm, 91 kg, 11% body fat), I aromatize like a crazy and I have all the above mentioned symptoms of high E2.
I’ve booked in a phone consultation with Dr. Saya, who advised me to introduce 0.1 mg of anastrazole in the mix, along with DHEA and pregnenolone to control my anxiety (I didn’t touch pregnenolone yet, because my serum levels are already in the mid-top range).
I started conservatively and took just 0.05 mg out of a vodka solution with anastrazole, and tested E2 2 weeks after, with just one dose taken the night before the blood test.
Well, my E2 went to 46.3 pg/mL, more than halved with a single dose of 0.05 mg! I started having some libido again, the gynecomastia went completely away, my memory and focus improved, my anxiety decreased substantially and I almost stopped sweating at night.
Probably my gene expression has changed with Finasteride (as Dr. Crisler was claiming), but with people like me, with such heavy aromatization, despite having a dialed in diet and heavy workout routine, I think a really small dose of anastrazole could be a game changer.
Unfortunately, some sides, like mild joints pain and liquid stools, have popped out again though.
I will test again my E2 an DHEA in 3 weeks and see how throwing in anastrazole and DHEA in the mix will change how I feel and the numbers.
I’m curious to know if someone else had a similar experience.
