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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Help keeping e2 up
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<blockquote data-quote="Cataceous" data-source="post: 191617" data-attributes="member: 38109"><p>It is a viable solution for increasing systemic levels while on TRT. I've done it. There are some uncertainties about doing this long-term. You're not creating the extra estradiol in the aromatase-containing tissues the way nature intended, so it may not be ideal.</p><p></p><p></p><p>The answer is "No", with caveats. For most, Clomid does not overcome negative feedback from testosterone at the hypothalamus. This means no LH to stimulate extra testosterone along with intratesticular aromatization. However, the zuclomiphene isomer of Clomid is estrogenic itself. This means it will activate some estrogen receptors, allowing it to do some of the same things estradiol does, such as increasing SHBG and improving bone density.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 191617, member: 38109"] It is a viable solution for increasing systemic levels while on TRT. I've done it. There are some uncertainties about doing this long-term. You're not creating the extra estradiol in the aromatase-containing tissues the way nature intended, so it may not be ideal. The answer is "No", with caveats. For most, Clomid does not overcome negative feedback from testosterone at the hypothalamus. This means no LH to stimulate extra testosterone along with intratesticular aromatization. However, the zuclomiphene isomer of Clomid is estrogenic itself. This means it will activate some estrogen receptors, allowing it to do some of the same things estradiol does, such as increasing SHBG and improving bone density. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Help keeping e2 up
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