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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
HELP - Heat Rashes, ED, and Cracking Joints - A journey Riddle with Side Effects
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<blockquote data-quote="Cataceous" data-source="post: 198934" data-attributes="member: 38109"><p>To the wisdom of the other's I'd add that you seem to be exerting only an indirect influence over the source of your issues. So if, for example, your problems were rooted in neurotransmitter imbalances then large testosterone doses could appear to work temporarily. As [USER=13851]@madman[/USER] notes, the honeymoon phenomenon is common with TRT, and may be due in part to dopaminergic effects. Without wanting to sound too pessimistic, I think you can fiddle with testosterone and estradiol till the cows come home and still maybe not end up where you want to be. TRT is a further mixed bag in that you're potentially disrupting a multitude of other hormones: LH, FSH, GnRH, kisspeptin, progesterone, DHEA and pregnenolone. The one positive is that if these hormones are out of kilter then there's less to lose by forcing them wherever you think they should be. What's your DHT like? You mention that prolactin is mid-range. What exactly? I've found that just having mine a few ng/mL over my baseline is enough to cause problems. Have you tried anything like trazodone, selegiline, cabergoline? Though it's restating the obvious: you need to home in on the aspects of the high testosterone dosing that are giving you the improvements—is it about neurotransmitters, perturbations to other hormones, etc.? If you develop and test some hypotheses then you'll be closer to finding a sustainable treatment.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 198934, member: 38109"] To the wisdom of the other's I'd add that you seem to be exerting only an indirect influence over the source of your issues. So if, for example, your problems were rooted in neurotransmitter imbalances then large testosterone doses could appear to work temporarily. As [USER=13851]@madman[/USER] notes, the honeymoon phenomenon is common with TRT, and may be due in part to dopaminergic effects. Without wanting to sound too pessimistic, I think you can fiddle with testosterone and estradiol till the cows come home and still maybe not end up where you want to be. TRT is a further mixed bag in that you're potentially disrupting a multitude of other hormones: LH, FSH, GnRH, kisspeptin, progesterone, DHEA and pregnenolone. The one positive is that if these hormones are out of kilter then there's less to lose by forcing them wherever you think they should be. What's your DHT like? You mention that prolactin is mid-range. What exactly? I've found that just having mine a few ng/mL over my baseline is enough to cause problems. Have you tried anything like trazodone, selegiline, cabergoline? Though it's restating the obvious: you need to home in on the aspects of the high testosterone dosing that are giving you the improvements—is it about neurotransmitters, perturbations to other hormones, etc.? If you develop and test some hypotheses then you'll be closer to finding a sustainable treatment. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
HELP - Heat Rashes, ED, and Cracking Joints - A journey Riddle with Side Effects
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