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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
HELP - Heat Rashes, ED, and Cracking Joints - A journey Riddle with Side Effects
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<blockquote data-quote="JustPanicNoDisco" data-source="post: 198772" data-attributes="member: 42100"><p>To preface this, I am a post-drug patient with lasting sexual side effects (yes, PFS, PSSD, and PAS exist and I will not argue this). </p><p></p><p>I have had enduring sexual dysfunction (dead libido, loss of morning wood, weak erections, etc.) for about 5 years since discontinuing psychiatric drugs. Most blood tests put me in LabCorp's mid range for TT, FT, E2, and prolactin. </p><p></p><p>Seeing that others in the post-drug community have seen success with elevating testosterone levels (and e2) much higher, I tried this approach. I started on 200mg/wk -- 30mg/day IM -- and had pretty great results, sexually, for the first 5-6 weeks. I had the returning of morning wood, my erection quality improved dramatically, I had libido again, and even the return of some long-lost emotions. However, after about week 5-6, I lost all benefits and seemed to become even worse (became extremely difficult to get an erection even with manual stimulation). </p><p></p><p>Labs showed TT over 1500, free T just over range, and E2 in reference range (LabCorp for male's 18-40). </p><p></p><p>The side effects on 200mg:</p><p></p><p> While running 200mg/wk, I had a slew of side effects mostly related a massive increase in adrenaline: loss of appetite, sleep issues, agitation, very bad anxiety (normally have zero), etc. Within the first week of starting, I also noticed the development of strange heat-induced rashes. These rashes felt and looked like strong allergic (histamine) reactions. In spite of switching from testosterone cypionate in cottonseed oil to test E in sesame oil, these rashes persisted. I thus concluded that these may be caused by higher estrogen levels (estrogen sensitizes mast cells and inhibits the DAO -- the main enzyme responsible for breaking down histamine). </p><p></p><p>Aside from the rashes, as mentioned above, I also developed ED after the initial 5-week or so honeymoon period. I have absolutely not idea how this happened. It didn't appear gradually but was quite abrupt. Thinking back on it now, it may have been related to taking antihistamines for the rash but I am not completely sure, as it still significantly seems erection quality is worse to this day. </p><p></p><p>Side effects on lower doses:</p><p></p><p>On lower doses of testosterone (I tried 160mg/wk, 140mg/wk, and 120mg/wk -- which i'm currently running), I experienced a reduction of negative adrenaline/norepinephrine-related side effects; however, I completely lost all sexual benefits and feel asexual again. In addition, I STILL have the rashes on 120mg/wk, which I consider something of a replacement dose (don't have bloods to confirm yet but will probably get them soon). Additionally, I've developed some low E2 symptoms I didn't have prior to starting TRT (namely, joint cracking/popping and joint pain). </p><p></p><p>This has been a very poor experience overall. I can't reap the benefits of high TRT because of the rashes, and on low doses, I am practically asexual, seem to be getting joint pain/cracking, and still have rashes (albeit less severe).</p><p></p><p>Has anyone encountered these heat-induced rashes and found a solution? Any other advice? I tried posting on what is probably considered the competitor TRT forum (won't post name here), and they didn't offer any solutions :/. </p><p></p><p>I'm quite knowledgeable about hormones in general. I did a LOT of reading prior to starting. I just didn't anticipate this many roadblocks.</p></blockquote><p></p>
[QUOTE="JustPanicNoDisco, post: 198772, member: 42100"] To preface this, I am a post-drug patient with lasting sexual side effects (yes, PFS, PSSD, and PAS exist and I will not argue this). I have had enduring sexual dysfunction (dead libido, loss of morning wood, weak erections, etc.) for about 5 years since discontinuing psychiatric drugs. Most blood tests put me in LabCorp's mid range for TT, FT, E2, and prolactin. Seeing that others in the post-drug community have seen success with elevating testosterone levels (and e2) much higher, I tried this approach. I started on 200mg/wk -- 30mg/day IM -- and had pretty great results, sexually, for the first 5-6 weeks. I had the returning of morning wood, my erection quality improved dramatically, I had libido again, and even the return of some long-lost emotions. However, after about week 5-6, I lost all benefits and seemed to become even worse (became extremely difficult to get an erection even with manual stimulation). Labs showed TT over 1500, free T just over range, and E2 in reference range (LabCorp for male's 18-40). The side effects on 200mg: While running 200mg/wk, I had a slew of side effects mostly related a massive increase in adrenaline: loss of appetite, sleep issues, agitation, very bad anxiety (normally have zero), etc. Within the first week of starting, I also noticed the development of strange heat-induced rashes. These rashes felt and looked like strong allergic (histamine) reactions. In spite of switching from testosterone cypionate in cottonseed oil to test E in sesame oil, these rashes persisted. I thus concluded that these may be caused by higher estrogen levels (estrogen sensitizes mast cells and inhibits the DAO -- the main enzyme responsible for breaking down histamine). Aside from the rashes, as mentioned above, I also developed ED after the initial 5-week or so honeymoon period. I have absolutely not idea how this happened. It didn't appear gradually but was quite abrupt. Thinking back on it now, it may have been related to taking antihistamines for the rash but I am not completely sure, as it still significantly seems erection quality is worse to this day. Side effects on lower doses: On lower doses of testosterone (I tried 160mg/wk, 140mg/wk, and 120mg/wk -- which i'm currently running), I experienced a reduction of negative adrenaline/norepinephrine-related side effects; however, I completely lost all sexual benefits and feel asexual again. In addition, I STILL have the rashes on 120mg/wk, which I consider something of a replacement dose (don't have bloods to confirm yet but will probably get them soon). Additionally, I've developed some low E2 symptoms I didn't have prior to starting TRT (namely, joint cracking/popping and joint pain). This has been a very poor experience overall. I can't reap the benefits of high TRT because of the rashes, and on low doses, I am practically asexual, seem to be getting joint pain/cracking, and still have rashes (albeit less severe). Has anyone encountered these heat-induced rashes and found a solution? Any other advice? I tried posting on what is probably considered the competitor TRT forum (won't post name here), and they didn't offer any solutions :/. I'm quite knowledgeable about hormones in general. I did a LOT of reading prior to starting. I just didn't anticipate this many roadblocks. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
HELP - Heat Rashes, ED, and Cracking Joints - A journey Riddle with Side Effects
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