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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
HELP - Doubts about TRT
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<blockquote data-quote="Phil Goodman" data-source="post: 279138" data-attributes="member: 42777"><p>Did they measure SHBG levels of the participants in that study, or are you just assuming that is what caused the variation? Did they measure SHBG levels in this study:</p><p></p><p>[URL unfurl="true"]https://www.sciencedirect.com/science/article/abs/pii/S1743609515307037[/URL]</p><p></p><p></p><p>Which stated this:</p><p></p><p>“In this study, daily application of testosterone 2% gel was effective at returning serum testosterone to physiologic levels in men with low testosterone and high BMI, although required dose was affected by BMI. ”</p><p></p><p></p><p></p><p></p><p>Also, people of the same weight can have different SHBG levels correct? So that would affect the amount of testosterone it would take to reach the same free t levels. Also, young men tend to have lower SHBG levels….so a young person with low SHBG producing 8 mg of test/day would end up with higher free t than an old man taking in 8 mg/test per day.</p><p></p><p></p><p></p><p></p><p>But, I’ll step away from this part of the discussion now as I don’t want to derail OP’s thread anymore than it already is since he is looking for legit guidance going forward.</p></blockquote><p></p>
[QUOTE="Phil Goodman, post: 279138, member: 42777"] Did they measure SHBG levels of the participants in that study, or are you just assuming that is what caused the variation? Did they measure SHBG levels in this study: [URL unfurl="true"]https://www.sciencedirect.com/science/article/abs/pii/S1743609515307037[/URL] Which stated this: “In this study, daily application of testosterone 2% gel was effective at returning serum testosterone to physiologic levels in men with low testosterone and high BMI, although required dose was affected by BMI. ” Also, people of the same weight can have different SHBG levels correct? So that would affect the amount of testosterone it would take to reach the same free t levels. Also, young men tend to have lower SHBG levels….so a young person with low SHBG producing 8 mg of test/day would end up with higher free t than an old man taking in 8 mg/test per day. But, I’ll step away from this part of the discussion now as I don’t want to derail OP’s thread anymore than it already is since he is looking for legit guidance going forward. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
HELP - Doubts about TRT
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