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<blockquote data-quote="Cataceous" data-source="post: 244532" data-attributes="member: 38109"><p>Welcome from another PeakTestosterone refugee! I'm sure you'll find ExcelMale is also a great place to be.</p><p></p><p>One of my focal points is on what normal dosing is with injections. I'm trying to correct a skewed mentality about this. You've been influenced to think that 60 mg of testosterone cypionate taken over a week is "pretty low". But it's not. The average testosterone production level for healthy young men corresponds to 60-70 mg of testosterone cypionate taken over a week. A normal full reference range of production would run from about 30-90 mg TC equivalent per week. Therefore doses much over 100 mg per week should be considered "pretty high". You are in good company in discovering that more is not better. See links to what others have said <a href="https://www.excelmale.com/forum/threads/feel-worse-with-higher-test-levels.26730/post-242470" target="_blank">here</a>.</p><p></p><p>Although still a hypothesis, it's considered likely that free testosterone levels are considerably more important than total testosterone. So it is important to see where you stand in this regard. If you have access to Quest then <a href="https://www.discountedlabs.com/testosterone-free-dialysis-and-total-ls-ms-ms" target="_blank">this test</a> from Discounted Labs is a good and affordable option. I recommend also measuring SHBG. With SHBG and total testosterone you can calculate free testosterone, which provides a check on the measured values, which are not 100% reliable. Our general expectation is that free testosterone should vary in proportion to dose. When you see changes in total testosterone at a dose that's nominally the same then it's possible that variance in SHBG is responsible rather than a change in potency of the products you're using.</p><p></p><p>If your SHBG is normal then it's less likely that further fiddling with testosterone would lead to dramatic improvements. A couple avenues for experimentation include adding hCG to your protocol or switching to a short-acting form of testosterone. HCG replaces the LH that is suppressed by TRT. It can reverse testicular atrophy and often restores fertility. Some feel it increases libido and provides other benefits. With hCG you want to use the lowest dose possible to avoid side effects.</p><p></p><p>Short-acting testosterone is of interest because, unlike conventional TRT, it allows continued HPTA function, making it less disruptive of many other hormones. Short-acting forms of testosterone include nasal gels and troches. Switching to these would be more intrusive than other changes, because it can take many months for the HPTA to normalize. But if you get through that then you could experience higher testosterone without HPTA suppression, which seems to be effective for many.</p><p></p><p>If you are ok with telemedicine then Defy Medical is another possible provider. Many of us use them and appreciate their good service and expertise. You might need to rein them in on dose recommendations, but they are very responsive to patients' preferences.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 244532, member: 38109"] Welcome from another PeakTestosterone refugee! I'm sure you'll find ExcelMale is also a great place to be. One of my focal points is on what normal dosing is with injections. I'm trying to correct a skewed mentality about this. You've been influenced to think that 60 mg of testosterone cypionate taken over a week is "pretty low". But it's not. The average testosterone production level for healthy young men corresponds to 60-70 mg of testosterone cypionate taken over a week. A normal full reference range of production would run from about 30-90 mg TC equivalent per week. Therefore doses much over 100 mg per week should be considered "pretty high". You are in good company in discovering that more is not better. See links to what others have said [URL='https://www.excelmale.com/forum/threads/feel-worse-with-higher-test-levels.26730/post-242470']here[/URL]. Although still a hypothesis, it's considered likely that free testosterone levels are considerably more important than total testosterone. So it is important to see where you stand in this regard. If you have access to Quest then [URL='https://www.discountedlabs.com/testosterone-free-dialysis-and-total-ls-ms-ms']this test[/URL] from Discounted Labs is a good and affordable option. I recommend also measuring SHBG. With SHBG and total testosterone you can calculate free testosterone, which provides a check on the measured values, which are not 100% reliable. Our general expectation is that free testosterone should vary in proportion to dose. When you see changes in total testosterone at a dose that's nominally the same then it's possible that variance in SHBG is responsible rather than a change in potency of the products you're using. If your SHBG is normal then it's less likely that further fiddling with testosterone would lead to dramatic improvements. A couple avenues for experimentation include adding hCG to your protocol or switching to a short-acting form of testosterone. HCG replaces the LH that is suppressed by TRT. It can reverse testicular atrophy and often restores fertility. Some feel it increases libido and provides other benefits. With hCG you want to use the lowest dose possible to avoid side effects. Short-acting testosterone is of interest because, unlike conventional TRT, it allows continued HPTA function, making it less disruptive of many other hormones. Short-acting forms of testosterone include nasal gels and troches. Switching to these would be more intrusive than other changes, because it can take many months for the HPTA to normalize. But if you get through that then you could experience higher testosterone without HPTA suppression, which seems to be effective for many. If you are ok with telemedicine then Defy Medical is another possible provider. Many of us use them and appreciate their good service and expertise. You might need to rein them in on dose recommendations, but they are very responsive to patients' preferences. [/QUOTE]
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