I would say even just anecdotally that I'm better with a much lower T dose, likewise my E is way down from where it was, etc etc I think you should look there, consider where your Free T is (over lab range?), your SHBG, and dose Cyp accordingly. I too did all the cardiologist stuff and was given a BB which I opted to not take, but I do better now than I was a year ago with my dosing and levels such as they were.