Heart Disease Risks in Women with PCOS: New Insights, Therapies, and Gaps in Research

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madman

madman

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In this webinar, Dr. Licy Yanes Cardozo presents the heightened cardiovascular risks in women with PCOS, the mechanisms underlying these risks, current treatments available, potential new therapies, and the existing knowledge gaps in women's health research.




Summary
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Summary II
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madman

Thread 'Groundbreaking Mount Sinai & Duke Study Links DNA Variants to Testosterone Overproduction in PCOS — Unlocking New Hope for Treatment'

Dr. Dunaif

* For the first time, we have shown how specific inherited DNA variants in PCOS change gene activity and increase testosterone production. That moves us from statistical association to biological mechanism.




Research could pave way for new therapies to treat polycystic ovary syndrome​

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www.mountsinai.org

Mount Sinai-Duke University Study Identifies DNA Variants That Increase Testosterone Production in PCOS Patients | Mount Sinai - New York

www.mountsinai.org

Journal: Nature Communications...
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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