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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
HCG timing
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<blockquote data-quote="Vince" data-source="post: 40359" data-attributes="member: 843"><p>What is the best dose of HCG? Dr Saya presents two case studies.</p><p></p><p> Read more at: <a href="https://www.excelmale.com/forum/showthread.php?6133-What-is-the-best-dose-of-HCG-Dr-Saya-presents-two-case-studiesA" target="_blank">https://www.excelmale.com/forum/showthread.php?6133-What-is-the-best-dose-of-HCG-Dr-Saya-presents-two-case-studiesA</a> single dosage of 500iu of hCG appears to exert a much more prolonged (and pronounced) increase in serum beta hCG concentrations, likely coinciding with a more prolonged and pronounced biological effect. Once again, whether this is beneficial or detrimental, can certainly be debated and will often hinge on many factors on an individualized case by case basis. It does appear obvious from the data that a dosage of 500iu of hCG will maintain levels >1mIU/mL for up to 3 days (72 hours) following a single injection. Thus, it would seem a direct conclusion to state that an hCG injection of 500iu every 3.5 days (twice weekly) would provide relatively continual stimulation of the leydig cells of the testes (concentration >1mIU/mL), and injections of this magnitude in dosage would NOT be needed any more frequently than that. My clinical mind and instincts suggest that the “ideal” hCG dosage likely lies in between these two extremes (150iu vs 500iu) and ideal frequency will hinge upon ideal dosage (with 150iu or less dosages likely requiring daily or even more frequent injections) and larger dosages (500iu, possibly even slightly smaller) requiring no more frequent than twice weekly injections, but this conclusion simply cannot be made concretely from this limited data. Furthermore, dosage decisions and frequencies are always individualized case-by-case based on many variables specific to the individual (fertility considerations, injection compliance, complicating factors such as SHBG levels, current/prior response to hCG, estradiol levels, testicular health, etc). Without specific data on other dosages (which I would like to obtain), these patterns suggest that a dosage regimen of hCG 250iu-350iu on an every other day (QOD) schedule would likely offer an alternative regimen for relatively steady and consistent testicular stimulation, although these conclusions are only speculative and cannot be drawn definitively from this limited data.</p><p></p><p> Read more at: <a href="https://www.excelmale.com/forum/showthread.php?6133-What-is-the-best-dose-of-HCG-Dr-Saya-presents-two-case-studies" target="_blank">https://www.excelmale.com/forum/showthread.php?6133-What-is-the-best-dose-of-HCG-Dr-Saya-presents-two-case-studies</a></p></blockquote><p></p>
[QUOTE="Vince, post: 40359, member: 843"] What is the best dose of HCG? Dr Saya presents two case studies. Read more at: [url]https://www.excelmale.com/forum/showthread.php?6133-What-is-the-best-dose-of-HCG-Dr-Saya-presents-two-case-studiesA[/url] single dosage of 500iu of hCG appears to exert a much more prolonged (and pronounced) increase in serum beta hCG concentrations, likely coinciding with a more prolonged and pronounced biological effect. Once again, whether this is beneficial or detrimental, can certainly be debated and will often hinge on many factors on an individualized case by case basis. It does appear obvious from the data that a dosage of 500iu of hCG will maintain levels >1mIU/mL for up to 3 days (72 hours) following a single injection. Thus, it would seem a direct conclusion to state that an hCG injection of 500iu every 3.5 days (twice weekly) would provide relatively continual stimulation of the leydig cells of the testes (concentration >1mIU/mL), and injections of this magnitude in dosage would NOT be needed any more frequently than that. My clinical mind and instincts suggest that the “ideal” hCG dosage likely lies in between these two extremes (150iu vs 500iu) and ideal frequency will hinge upon ideal dosage (with 150iu or less dosages likely requiring daily or even more frequent injections) and larger dosages (500iu, possibly even slightly smaller) requiring no more frequent than twice weekly injections, but this conclusion simply cannot be made concretely from this limited data. Furthermore, dosage decisions and frequencies are always individualized case-by-case based on many variables specific to the individual (fertility considerations, injection compliance, complicating factors such as SHBG levels, current/prior response to hCG, estradiol levels, testicular health, etc). Without specific data on other dosages (which I would like to obtain), these patterns suggest that a dosage regimen of hCG 250iu-350iu on an every other day (QOD) schedule would likely offer an alternative regimen for relatively steady and consistent testicular stimulation, although these conclusions are only speculative and cannot be drawn definitively from this limited data. Read more at: [URL]https://www.excelmale.com/forum/showthread.php?6133-What-is-the-best-dose-of-HCG-Dr-Saya-presents-two-case-studies[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
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