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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
HCG: Storage, Travel, Potency
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<blockquote data-quote="tonyfr" data-source="post: 69842" data-attributes="member: 15055"><p>Actually, I spent a few hours on web searches, so I did skip the forum search. Some of the issues I mentioned were not covered in any of the discussions I saw.</p><p></p><p>For instance, there is a lot of discussion about freezing HCG, but not much discussion of sterility. </p><p></p><p>I decided to search this forum specifically.</p><p></p><p><strong>Regarding freezing HCG</strong>, Dr. Saya (DefyMedical) says: "Once reconstituted, the general recommendation is to NOT freeze, however damage to the peptide likely increases proportional to the number of freeze-thaw cycles. In other words, if you are keeping it to only ONE freeze-thaw cycle there should be far less potential damage to the peptide than for more/repetitive freeze-thaw cycles."</p><p></p><p>Which leaves the question open whether it would be better to freeze HCG and thaw 3 weeks later or just refrigerate for 3 weeks (e.g. you go on vacation for 3 weeks and leave the HCG behind). In both cases, some degradation will occur. It's clear no one will be able to answer which method results in the least degradation. </p><p></p><p><strong>Regarding pre-filled syringes</strong>, I've found only one comment addressing the sterility issue (from Jasen Bruce, moderator): "It is not recommended to pre-load syringes for storage. To preserve potency and sterility during storage the syringe needs to be loaded in a sterile environment, such as under a hood. Contamination occurs when you are transferring within a non-sterile environment which then reduces the shelf-life/stability of the medication." I am surprised at the general lack of concern for sterility.</p><p></p><p><strong>Regarding vibration damage during travel</strong>, well, the only post I could find even mentioning vibration is mine. I tried other searches and found this comment by Super Moderator Gene Devine: "Fellows - The online concept that HCG is "fragile" and can damage the drug if shaken excessively is lure! If you knew the brutal process of how the drug is manufactured you wouldn't believe it...and guess what? When you get it and reconstitute it...it works! Don't worry about the shaking it will go through when traveling as it will not hurt the potency of the drug whatsoever!" I'm not sure what he means by "lure" (typo?) and also unclear whether he is referring to traveling with the powdered HCG or reconstituted HCG.</p><p></p><p><strong>Regarding testing HCG for potency</strong>, I can't find any topic that looks like it addresses this issue. I would assume it can't be done if I hadn't seen one web posting (somewhere—can't remember where) in which a woman mentioned checking her HCG potency (she didn't mention how). Follow-up searching found an article claiming that a pregnancy test kit could be used to test HCG potency, but later retracting the claim.</p><p></p><p>So, the one issue that maybe hasn't been talked to death is vibration/shaking during travel. My doctor (from DefyMedical) said not to store HCG on the refrigerator door, not because of the temperature fluctuations, but because it shakes the medicine around. If that's true, it's not going to survive a plane trip, followed by days of driving around on various types of roads.</p></blockquote><p></p>
[QUOTE="tonyfr, post: 69842, member: 15055"] Actually, I spent a few hours on web searches, so I did skip the forum search. Some of the issues I mentioned were not covered in any of the discussions I saw. For instance, there is a lot of discussion about freezing HCG, but not much discussion of sterility. I decided to search this forum specifically. [B]Regarding freezing HCG[/B], Dr. Saya (DefyMedical) says: "Once reconstituted, the general recommendation is to NOT freeze, however damage to the peptide likely increases proportional to the number of freeze-thaw cycles. In other words, if you are keeping it to only ONE freeze-thaw cycle there should be far less potential damage to the peptide than for more/repetitive freeze-thaw cycles." Which leaves the question open whether it would be better to freeze HCG and thaw 3 weeks later or just refrigerate for 3 weeks (e.g. you go on vacation for 3 weeks and leave the HCG behind). In both cases, some degradation will occur. It's clear no one will be able to answer which method results in the least degradation. [B]Regarding pre-filled syringes[/B], I've found only one comment addressing the sterility issue (from Jasen Bruce, moderator): "It is not recommended to pre-load syringes for storage. To preserve potency and sterility during storage the syringe needs to be loaded in a sterile environment, such as under a hood. Contamination occurs when you are transferring within a non-sterile environment which then reduces the shelf-life/stability of the medication." I am surprised at the general lack of concern for sterility. [B]Regarding vibration damage during travel[/B], well, the only post I could find even mentioning vibration is mine. I tried other searches and found this comment by Super Moderator Gene Devine: "Fellows - The online concept that HCG is "fragile" and can damage the drug if shaken excessively is lure! If you knew the brutal process of how the drug is manufactured you wouldn't believe it...and guess what? When you get it and reconstitute it...it works! Don't worry about the shaking it will go through when traveling as it will not hurt the potency of the drug whatsoever!" I'm not sure what he means by "lure" (typo?) and also unclear whether he is referring to traveling with the powdered HCG or reconstituted HCG. [B]Regarding testing HCG for potency[/B], I can't find any topic that looks like it addresses this issue. I would assume it can't be done if I hadn't seen one web posting (somewhere—can't remember where) in which a woman mentioned checking her HCG potency (she didn't mention how). Follow-up searching found an article claiming that a pregnancy test kit could be used to test HCG potency, but later retracting the claim. So, the one issue that maybe hasn't been talked to death is vibration/shaking during travel. My doctor (from DefyMedical) said not to store HCG on the refrigerator door, not because of the temperature fluctuations, but because it shakes the medicine around. If that's true, it's not going to survive a plane trip, followed by days of driving around on various types of roads. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
HCG: Storage, Travel, Potency
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